{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T02:24:17Z","timestamp":1791685457644,"version":"4.3.4"},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2015,12,10]],"date-time":"2015-12-10T00:00:00Z","timestamp":1449705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010425","name":"Tri-Service General Hospital","doi-asserted-by":"crossref","award":["TSGH-C104-109"],"award-info":[{"award-number":["TSGH-C104-109"]}],"id":[{"id":"10.13039\/501100010425","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2016,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>Three recent studies demonstrated the positive effect of extracorporeal shock wave therapy (ESWT) for treating carpal tunnel syndrome (CTS). However, none have entirely proved the effects of ESWT on CTS because all studies had a small sample size and lacked a placebo\u2010controlled design. Moreover, radial ESWT (rESWT) has not been used to treat CTS. We conducted a prospective randomized, controlled, double\u2010blinded study to assess the effect of rESWT for treating CTS. Thirty\u2010four enrolled patients (40 wrists) were randomized into intervention and control groups (20 wrists in each). Participants in the intervention group underwent three sessions of rESWT with nightly splinting, whereas those in the control group underwent sham rESWT with nightly splinting. The primary outcome was visual analog scale (VAS), whereas the secondary outcomes included the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ), cross\u2010sectional area (CSA) of the median nerve, sensory nerve conduction velocity of the median nerve, and finger pinch strength. Evaluations were performed before treatment and at 1, 4, 8, and 12 weeks after the third rESWT session. A significantly greater improvement in the VAS, BCTQ scores, and CSA of the median nerve was noted in the intervention group throughout the study as compared to the control group (except for BCTQ severity at week 12 and CSA at weeks 1 and 4) (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). This is the first study to assess rESWT in a randomized placebo\u2010controlled trial and demonstrate that rESWT is a safe and effective method for relieving pain and disability in patients with CTS. \u00a9 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:977\u2013984, 2016.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jor.23113","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T17:02:41Z","timestamp":1448557361000},"page":"977-984","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":67,"title":["Effect of radial shock wave therapy for carpal tunnel syndrome: A prospective randomized, double\u2010blind, placebo\u2010controlled trial"],"prefix":"10.1002","volume":"34","author":[{"given":"Yung\u2010Tsan","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation Tri\u2010Service General Hospital School of Medicine National Defense Medical Center No. 325, Sec. 2 Cheng\u2010Kung Road Neihu District Taipei Taiwan Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming\u2010Jen","family":"Ke","sequence":"additional","affiliation":[{"name":"Department of 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