{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T14:26:47Z","timestamp":1791556007409,"version":"4.3.4"},"reference-count":52,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T00:00:00Z","timestamp":1484438400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T00:00:00Z","timestamp":1484438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"UTMB Claude D. Pepper Older Americans 394 Independence Center NIH\/NIA","award":["P30 AG024832"],"award-info":[{"award-number":["P30 AG024832"]}]},{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["K23 AR062069"],"award-info":[{"award-number":["K23 AR062069"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Orthop. Res."],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1002\/jor.23502","type":"journal-article","created":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T12:16:44Z","timestamp":1481285804000},"page":"1876-1885","source":"Crossref","is-referenced-by-count":80,"title":["ACL injury reduces satellite cell abundance and promotes fibrogenic cell expansion within skeletal muscle"],"prefix":"10.1002","volume":"35","author":[{"given":"Christopher S.","family":"Fry","sequence":"first","affiliation":[{"name":"Department of Nutrition and Metabolism; University of Texas Medical Branch; Galveston TX 77555"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darren L.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine; University of Kentucky; Lexington KY 40536"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Lloyd","family":"Ireland","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine; University of Kentucky; Lexington KY 40536"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Noehren","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine; University of Kentucky; Lexington KY 40536"},{"name":"Division of Physical Therapy; University of Kentucky; Lexington KY 40536"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,1,15]]},"reference":[{"key":"10.1002\/jor.23502-BIB0001|jor23502-cit-0001","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1177\/0363546506286866","article-title":"Understanding and preventing noncontact anterior cruciate ligament injuries: a review of the Hunt Valley II meeting, January 2005","volume":"34","author":"Griffin","year":"2006","journal-title":"Am J Sports Med"},{"key":"10.1002\/jor.23502-BIB0002|jor23502-cit-0002","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/JES.0b013e3181f450b4","article-title":"Complex integrative morphological and mechanical contributions to ACL injury risk","volume":"38","author":"McLean","year":"2010","journal-title":"Exer Sport Sci Rev"},{"key":"10.1002\/jor.23502-BIB0003|jor23502-cit-0003","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1097\/00005768-200008000-00016","article-title":"Knee strength deficits after hamstring tendon and patellar tendon anterior cruciate ligament reconstruction","volume":"32","author":"Hiemstra","year":"2000","journal-title":"Med Sci Sports Exer"},{"key":"10.1002\/jor.23502-BIB0004|jor23502-cit-0004","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1097\/00005768-199810000-00003","article-title":"Gait biomechanics are not normal after anterior cruciate ligament reconstruction and accelerated rehabilitation","volume":"30","author":"DeVita","year":"1998","journal-title":"Med Sci Sports Exer"},{"key":"10.1002\/jor.23502-BIB0005|jor23502-cit-0005","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/JSM.0b013e31804c77ea","article-title":"Limb asymmetries in landing and jumping 2 years following anterior cruciate ligament reconstruction","volume":"17","author":"Paterno","year":"2007","journal-title":"Clin J Sport Med"},{"key":"10.1002\/jor.23502-BIB0006|jor23502-cit-0006","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/jor.20472","article-title":"Neuromuscular adaptations and correlates of knee functionality following ACL reconstruction","volume":"26","author":"Bryant","year":"2008","journal-title":"J Orthop Res"},{"key":"10.1002\/jor.23502-BIB0007|jor23502-cit-0007","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.clinbiomech.2010.09.011","article-title":"Alterations in joint kinematics during walking following hamstring and patellar tendon anterior cruciate ligament reconstruction surgery","volume":"26","author":"Webster","year":"2011","journal-title":"Clin Biomech"},{"key":"10.1002\/jor.23502-BIB0008|jor23502-cit-0008","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1177\/03635465030310041501","article-title":"A randomized comparison of patellar tendon and hamstring tendon anterior cruciate ligament reconstruction","volume":"31","author":"Feller","year":"2003","journal-title":"Am J Sports Med"},{"key":"10.1002\/jor.23502-BIB0009|jor23502-cit-0009","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1177\/03635465030310010501","article-title":"A prospective randomized study of patellar versus hamstring tendon autografts for anterior cruciate ligament reconstruction","volume":"31","author":"Jansson","year":"2003","journal-title":"Am J Sports Med"},{"key":"10.1002\/jor.23502-BIB0010|jor23502-cit-0010","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1177\/0363546506294361","article-title":"A prospective randomized study of anterior cruciate ligament reconstruction: a comparison of patellar tendon and quadruple-strand semitendinosus\/gracilis tendons fixed with bioabsorbable interference screws","volume":"35","author":"Maletis","year":"2007","journal-title":"Am J Sports Med"},{"key":"10.1002\/jor.23502-BIB0011|jor23502-cit-0011","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1055\/s-2007-972836","article-title":"Isokinetic muscle performance after anterior cruciate ligament surgery. Long-term results and outcome predicting factors after primary surgery and late-phase reconstruction","volume":"17","author":"Natri","year":"1996","journal-title":"Int J Sports Med"},{"key":"10.1002\/jor.23502-BIB0012|jor23502-cit-0012","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/j.csm.2008.02.001","article-title":"Maximizing quadriceps strength after ACL reconstruction","volume":"27","author":"Palmieri-Smith","year":"2008","journal-title":"Clin Sports Med"},{"key":"10.1002\/jor.23502-BIB0013|jor23502-cit-0013","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.2106\/00004623-199508000-00004","article-title":"Strength of the quadriceps femoris muscle and functional recovery after reconstruction of the anterior cruciate ligament. A prospective, randomized clinical trial of electrical stimulation","volume":"77","author":"Snyder-Mackler","year":"1995","journal-title":"J Bone Joint Surg Am"},{"key":"10.1002\/jor.23502-BIB0014|jor23502-cit-0014","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s002640100268","article-title":"Patellar tendon vs. doubled semitendinosus and gracilis tendon for anterior cruciate ligament reconstruction","volume":"25","author":"Witvrouw","year":"2001","journal-title":"Int Orthop"},{"key":"10.1002\/jor.23502-BIB0015|jor23502-cit-0015","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1111\/j.1600-0838.2011.01417.x","article-title":"Functional and muscle morphometric effects of ACL reconstruction. A prospective CT study with 1 year follow-up","volume":"23","author":"Lindstr\u00f6m","year":"2011","journal-title":"Scand J Med Sci Sports"},{"key":"10.1002\/jor.23502-BIB0016|jor23502-cit-0016","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1177\/0363546511422999","article-title":"Return-to-Sport outcomes at 2 to 7 years after anterior cruciate ligament reconstruction surgery","volume":"40","author":"Ardern","year":"2012","journal-title":"Am J Sports Med"},{"key":"10.1002\/jor.23502-BIB0017|jor23502-cit-0017","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.2106\/JBJS.16.00035","article-title":"Cellular and morphological alterations in the vastus lateralis muscle as the result of ACL injury and reconstruction","volume":"98","author":"Noehren","year":"2016","journal-title":"J Bone Joint Surg Am"},{"key":"10.1002\/jor.23502-BIB0018|jor23502-cit-0018","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1096\/fj.13-239426","article-title":"Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy","volume":"28","author":"Fry","year":"2014","journal-title":"FASEB J"},{"key":"10.1002\/jor.23502-BIB0019|jor23502-cit-0019","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1097\/nen.0b013e3181634ef7","article-title":"Muscle interstitial fibroblasts are the main source of collagen VI synthesis in skeletal muscle: implications for congenital muscular dystrophy types Ullrich and Bethlem","volume":"67","author":"Zou","year":"2008","journal-title":"J Neuropathol Exp Neurol"},{"key":"10.1002\/jor.23502-BIB0020|jor23502-cit-0020","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1242\/dev.064162","article-title":"Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration","volume":"138","author":"Murphy","year":"2011","journal-title":"Development"},{"key":"10.1002\/jor.23502-BIB0021|jor23502-cit-0021","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1242\/jcs.086629","article-title":"Fibrosis and adipogenesis originate from a common mesenchymal progenitor in skeletal muscle","volume":"124","author":"Uezumi","year":"2011","journal-title":"J Cell Sci"},{"key":"10.1002\/jor.23502-BIB0022|jor23502-cit-0022","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1038\/nm.2848","article-title":"Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury","volume":"18","author":"Dulauroy","year":"2012","journal-title":"Nat Med"},{"key":"10.1002\/jor.23502-BIB0023|jor23502-cit-0023","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.devcel.2008.12.003","article-title":"Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis","volume":"16","author":"Olson","year":"2009","journal-title":"Dev Cell"},{"key":"10.1002\/jor.23502-BIB0024|jor23502-cit-0024","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1113\/jphysiol.2014.271288","article-title":"Fibre type-specific satellite cell response to aerobic training in sedentary adults","volume":"592","author":"Fry","year":"2014","journal-title":"J Physiol"},{"key":"10.1002\/jor.23502-BIB0025|jor23502-cit-0025","doi-asserted-by":"crossref","first-page":"5223","DOI":"10.1113\/JP272520","article-title":"Satellite cell activation and apoptosis in skeletal muscle from severely burned children","volume":"594","author":"Fry","year":"2016","journal-title":"J Physiol"},{"key":"10.1002\/jor.23502-BIB0026|jor23502-cit-0026","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1152\/japplphysiol.00848.2013","article-title":"Automated fiber-type-specific cross-sectional area assessment and myonuclei counting in skeletal muscle","volume":"115","author":"Liu","year":"2013","journal-title":"J Appl Physiol"},{"key":"10.1002\/jor.23502-BIB0027|jor23502-cit-0027","doi-asserted-by":"crossref","first-page":"e1186","DOI":"10.1038\/cddis.2014.161","article-title":"Identification and characterization of PDGFRalpha+ mesenchymal progenitors in human skeletal muscle","volume":"5","author":"Uezumi","year":"2014","journal-title":"Cell Death Dis"},{"key":"10.1002\/jor.23502-BIB0028|jor23502-cit-0028","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1152\/japplphysiol.00799.2015","article-title":"Fourteen days of bed rest induces a decline in satellite cell content and robust atrophy of skeletal muscle fibers in middle-aged adults","volume":"120","author":"Arentson-Lantz","year":"2016","journal-title":"J Appl Physiol"},{"key":"10.1002\/jor.23502-BIB0029|jor23502-cit-0029","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s11357-013-9583-2","article-title":"Satellite cells in human skeletal muscle; from birth to old age","volume":"36","author":"Verdijk","year":"2013","journal-title":"Age (Dordr)"},{"key":"10.1002\/jor.23502-BIB0030|jor23502-cit-0030","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1042\/bj2900641","article-title":"Age-related changes in expression of the neural cell adhesion molecule in skeletal muscle: a comparative study of newborn, adult and aged rats","volume":"290 (Pt 3)","author":"Andersson","year":"1993","journal-title":"Biochem J"},{"key":"10.1002\/jor.23502-BIB0031|jor23502-cit-0031","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/jemt.1170","article-title":"Expression of Leu-19 (CD56, N-CAM) and nitric oxide synthase (NOS) I in denervated and reinnervated human skeletal muscle","volume":"55","author":"Gosztonyi","year":"2001","journal-title":"Microsc Res Tech"},{"key":"10.1002\/jor.23502-BIB0032|jor23502-cit-0032","doi-asserted-by":"crossref","first-page":"722","DOI":"10.2522\/ptj.20150029","article-title":"Developmental biology and regenerative medicine: addressing the vexing problem of persistent muscle atrophy in the chronically torn human rotator cuff","volume":"96","author":"Meyer","year":"2016","journal-title":"Phys Ther"},{"key":"10.1002\/jor.23502-BIB0033|jor23502-cit-0033","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1038\/ncomms2964","article-title":"Collagen VI regulates satellite cell self-renewal and muscle regeneration","volume":"4","author":"Urciuolo","year":"2013","journal-title":"Nat Commun"},{"key":"10.1002\/jor.23502-BIB0034|jor23502-cit-0034","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1126\/science.1191035","article-title":"Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture","volume":"329","author":"Gilbert","year":"2010","journal-title":"Science"},{"key":"10.1002\/jor.23502-BIB0035|jor23502-cit-0035","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/s12015-007-9000-2","article-title":"Intrinsic changes and extrinsic influences of myogenic stem cell function during aging","volume":"3","author":"Brack","year":"2007","journal-title":"Stem Cell Rev"},{"key":"10.1002\/jor.23502-BIB0036|jor23502-cit-0036","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/2044-5040-1-21","article-title":"Aberrant repair and fibrosis development in skeletal muscle","volume":"1","author":"Mann","year":"2011","journal-title":"Skelet Muscle"},{"key":"10.1002\/jor.23502-BIB0037|jor23502-cit-0037","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/ncb2014","article-title":"Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle","volume":"12","author":"Uezumi","year":"2010","journal-title":"Nat Cell Biol"},{"key":"10.1002\/jor.23502-BIB0038|jor23502-cit-0038","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1152\/japplphysiol.01108.2014","article-title":"Pericyte response to contraction mode-specific resistance exercise training in human skeletal muscle","volume":"119","author":"Farup","year":"2015","journal-title":"J Appl Physiol"},{"key":"10.1002\/jor.23502-BIB0039|jor23502-cit-0039","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/ncb2015","article-title":"Muscle injury activates resident fibro\/adipogenic progenitors that facilitate myogenesis","volume":"12","author":"Joe","year":"2010","journal-title":"Nat Cell Biol"},{"key":"10.1002\/jor.23502-BIB0040|jor23502-cit-0040","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1242\/dev.057463","article-title":"Connective tissue fibroblasts and Tcf4 regulate myogenesis","volume":"138","author":"Mathew","year":"2011","journal-title":"Development"},{"key":"10.1002\/jor.23502-BIB0041|jor23502-cit-0041","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1242\/dev.064162","article-title":"Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration","volume":"138","author":"Murphy","year":"2011","journal-title":"Development"},{"key":"10.1002\/jor.23502-BIB0042|jor23502-cit-0042","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3389\/fphys.2014.00068","article-title":"Roles of nonmyogenic mesenchymal progenitors in pathogenesis and regeneration of skeletal muscle","volume":"5","author":"Uezumi","year":"2014","journal-title":"Front Physiol"},{"key":"10.1002\/jor.23502-BIB0043|jor23502-cit-0043","doi-asserted-by":"crossref","first-page":"4894","DOI":"10.1073\/pnas.85.13.4894","article-title":"Transforming growth factor-beta stimulates collagen-matrix contraction by fibroblasts-implications for wound-healing","volume":"85","author":"Montesano","year":"1988","journal-title":"Proc Nat Acad Sci USA"},{"key":"10.1002\/jor.23502-BIB0044|jor23502-cit-0044","doi-asserted-by":"crossref","first-page":"3657","DOI":"10.1242\/dev.068858","article-title":"Effective fiber hypertrophy in satellite cell-depleted skeletal muscle","volume":"138","author":"McCarthy","year":"2011","journal-title":"Development"},{"key":"10.1002\/jor.23502-BIB0045|jor23502-cit-0045","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1002\/ar.1091700405","article-title":"Satellite cells as the source of nuclei in muscles of growing rats","volume":"170","author":"Moss","year":"1971","journal-title":"Anat Rec"},{"key":"10.1002\/jor.23502-BIB0046|jor23502-cit-0046","doi-asserted-by":"crossref","first-page":"7479","DOI":"10.1073\/pnas.0811129106","article-title":"Muscle hypertrophy driven by myostatin blockade does not require stem\/precursor-cell activity","volume":"106","author":"Amthor","year":"2009","journal-title":"Proc Nat Acad Sci USA"},{"key":"10.1002\/jor.23502-BIB0047|jor23502-cit-0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2016.09.010","article-title":"Myogenic progenitor cells control extracellular matrix production by fibroblasts during skeletal muscle hypertrophy","author":"Fry","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1002\/jor.23502-BIB0048|jor23502-cit-0048","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1093\/gerona\/glv176","article-title":"Resistance training enhances skeletal muscle innervation without modifying the number of satellite cells or their myofiber association in obese older adults","volume":"71","author":"Messi","year":"2015","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1002\/jor.23502-BIB0049|jor23502-cit-0049","doi-asserted-by":"crossref","first-page":"E937","DOI":"10.1152\/ajpendo.00190.2006","article-title":"Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and women","volume":"291","author":"Petrella","year":"2006","journal-title":"Am J Physiol Endocrinol Metabol"},{"key":"10.1002\/jor.23502-BIB0050|jor23502-cit-0050","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1152\/japplphysiol.01215.2007","article-title":"Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis","volume":"104","author":"Petrella","year":"2008","journal-title":"J Appl Physiol"},{"key":"10.1002\/jor.23502-BIB0051|jor23502-cit-0051","doi-asserted-by":"crossref","first-page":"R1288","DOI":"10.1152\/ajpregu.00576.2004","article-title":"Age-related differences in apoptosis with disuse atrophy in soleus muscle","volume":"288","author":"Leeuwenburgh","year":"2005","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1002\/jor.23502-BIB0052|jor23502-cit-0052","doi-asserted-by":"crossref","first-page":"C981","DOI":"10.1152\/ajpcell.00298.2005","article-title":"Mechanical load-dependent regulation of satellite cell and fiber size in rat soleus muscle","volume":"290","author":"Wang","year":"2006","journal-title":"Am J Physiol Cell Physiol"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjor.23502","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/jor.23502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T11:48:11Z","timestamp":1625485691000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.23502"}},"subtitle":["ACL INJURY INDUCES MUSCLE MALADAPTATIONS"],"short-title":[],"issued":{"date-parts":[[2017,1,15]]},"references-count":52,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,9]]}},"URL":"https:\/\/doi.org\/10.1002\/jor.23502","archive":["Portico"],"relation":{},"ISSN":["0736-0266"],"issn-type":[{"value":"0736-0266","type":"print"}],"subject":[],"published":{"date-parts":[[2017,1,15]]}}}