{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:39:10Z","timestamp":1790638750688,"version":"4.1.0"},"reference-count":52,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2017,4,17]],"date-time":"2017-04-17T00:00:00Z","timestamp":1492387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["BA 3347\/3\u20101"],"award-info":[{"award-number":["BA 3347\/3\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["BA 3347\/3\u20102"],"award-info":[{"award-number":["BA 3347\/3\u20102"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WO 452\/8\u20101"],"award-info":[{"award-number":["WO 452\/8\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["WO 452\/8\u20102"],"award-info":[{"award-number":["WO 452\/8\u20102"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2017,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>Since dislocation of total hip replacements (THR) remains a clinical problem, its mechanisms are still in the focus of research. Previous studies ignored the impact of soft tissue structures and dynamic processes or relied on simplified joint contact mechanics, thus, hindered a thorough understanding. Therefore, the purpose of the present study was to use hardware\u2010in\u2010the\u2010loop (HiL) simulation to analyze systematically the impact of varying implant positions and designs as well as gluteal and posterior muscle function on THR instability under physiological\u2010like loading conditions during dynamic movements. A musculoskeletal multibody model emulated the in situ environment of the lower extremity during deep sit\u2010to\u2010stand with femoral adduction maneuver while a six\u2010axis robot moved and loaded a THR accordingly to feed physical measurements back to the multibody model. Commercial THRs with hard\u2010soft bearings were used in the simulation with three different head diameters (28, 36, 44\u2009mm) and two offsets (M, XL). Cup inclination of 45\u00b0, cup anteversion of 20\u00b0, and stem anteversion of 10\u00b0 revealed to be outstandingly robust against any instability\u2010related parameter variation. For the flexion motion, higher combined anteversion angles of cup and stem seemed generally favorable. Total hip instability was either deferred or even avoided even in the presence of higher cup inclination. Larger head diameters (&gt;36\u2009mm) and femoral head offsets (8\u2009mm) deferred occurrence of prosthetic and bone impingement associated with increasing resisting torques. In summary, implant positioning had a much higher impact on total hip stability than gluteal insufficiency and impaired muscle function. \u00a9 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2557\u20132566, 2017.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jor.23549","type":"journal-article","created":{"date-parts":[[2017,2,24]],"date-time":"2017-02-24T09:42:40Z","timestamp":1487929360000},"page":"2557-2566","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Dynamical analysis of dislocation\u2010associated factors in total hip replacements by hardware\u2010in\u2010the\u2010loop simulation"],"prefix":"10.1002","volume":"35","author":[{"given":"Andreas","family":"Geier","sequence":"first","affiliation":[{"name":"Department of Orthopaedics University Medicine of Rostock Doberaner Stra\u00dfe 142 D\u201018057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Kluess","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University Medicine of Rostock Doberaner Stra\u00dfe 142 D\u201018057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Grawe","sequence":"additional","affiliation":[{"name":"Chair of Technical Dynamics University of Rostock Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University Medicine of Rostock Doberaner Stra\u00dfe 142 D\u201018057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darryl","family":"D'Lima","sequence":"additional","affiliation":[{"name":"Shiley Center for Orthopaedic Research and Education at Scripps Clinic La Jolla California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Woernle","sequence":"additional","affiliation":[{"name":"Chair of Technical Dynamics University of Rostock Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Bader","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University Medicine of Rostock Doberaner Stra\u00dfe 142 D\u201018057 Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,17]]},"reference":[{"key":"e_1_2_7_2_1","article-title":"Swedish hip arthroplasty register, Gothenburg, Sweden","author":"Garellick G","year":"2013","journal-title":"Annual Report"},{"key":"e_1_2_7_3_1","article-title":"National hospital discharge survey: 2005 annual summary with detailed diagnosis and procedure data","author":"DeFrances CJ","year":"2007","journal-title":"Vital Health Stat 13"},{"key":"e_1_2_7_4_1","unstructured":"Centers for Disease Control and Prevention National Center for Health Statistics. 2010. Number of all\u2010listed procedures for discharges from short\u2010stay hospitals by ICD\u20109\u2010CM code sex age and geographic region. United States Hyattsville Maryland."},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.00155"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2004.07.008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2006.07.001"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200003000-00003"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1515\/bmte.1999.44.7-8.212"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2005.04.003"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2004.03.012"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1515\/bmt.2010.005"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1515\/BMT.2004.027"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1109\/ICCAS.2008.4694415"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2013.09.007"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199810000-00016"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-5898(05)70226-1"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200009000-00010"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2011.04.002"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(01)00096-1"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(02)00232-4"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2004.09.004"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197860020-00014"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21524"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-014-3818-0"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(01)00053-5"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200112000-00019"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200210000-00009"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200403000-00027"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000218746.84494.df"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.21435"},{"key":"e_1_2_7_32_1","volume-title":"Dynamic testing of total hip and knee replacements under physiological conditions","author":"Herrmann S","year":"2015"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0145798"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-01947-0_20"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11044-011-9283-6"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2011.07.012"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-09411-3_70"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/jamia.1996.96236280"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(01)00222-6"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(02)00336-6"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2004.05.042"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2006.10.003"},{"key":"e_1_2_7_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-008-0594-8"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(89)90227-3"},{"key":"e_1_2_7_45_1","article-title":"Impact of the patella height on the strain pattern of the medial patellofemoral ligament after reconstruction: a computer model\u2010based study","author":"Tischer T","year":"2016","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"e_1_2_7_46_1","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1302\/0301-620X.75B2.8444942","article-title":"The definition and measurement of acetabular orientation","volume":"75","author":"Murray D","year":"1993","journal-title":"J Bone Joint Surg Am"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.87B6.14745"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(90)90065-B"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22127"},{"key":"e_1_2_7_50_1","first-page":"336","article-title":"Cup positioning in total hip arthroplasty","author":"Scheerlinck T","year":"2014","journal-title":"Acta Orthop Belg"},{"key":"e_1_2_7_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22659"},{"key":"e_1_2_7_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2012.04.057"},{"key":"e_1_2_7_53_1","first-page":"130","article-title":"The impact of capsular repair on the dislocation rate after primary total hip arthroplasty: a retrospective analysis of 1972 cases","volume":"152","author":"Prietzel T","year":"2014","journal-title":"Z Orthop Unfall"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjor.23549","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.23549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T02:59:47Z","timestamp":1696388387000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.23549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,17]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11]]}},"alternative-id":["10.1002\/jor.23549"],"URL":"https:\/\/doi.org\/10.1002\/jor.23549","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,17]]},"assertion":[{"value":"2016-07-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-02-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}