{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T21:59:43Z","timestamp":1788559183240,"version":"build-2803163510"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T00:00:00Z","timestamp":1553731200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Diagnostic monitoring and prediction of bone fracture healing is critical for the detection of delayed union or non\u2010union and provides the requisite information as to whether therapeutic intervention or timely revision are warranted. A promising approach to monitor fracture healing is to measure the mechanical load\u2010sharing between the healing callus and the implanted hardware used for internal fixation. The objectives of this study were to evaluate a non\u2010invasive measurement system in which an antenna electromagnetically couples with the implanted hardware to sense deflections of the hardware due to an applied load and to investigate the efficacy of the system to detect changes in mechanical load\u2010sharing in an ex vivo fracture healing model. The measurement system was applied to ovine metatarsal bones treated with osteotomies, resulting in four different levels of bone stability which simulated various degrees of fracture healing. Computational finite element simulations supplemented these ex vivo experiments to compare the osteotomy model of fracture healing to a more clinically applicable callus stiffening model of healing. In the ex vivo experiments, the electromagnetic coupling system detected significant differences between the four simulated degrees of healing with good repeatability. Computational simulations indicated that the experimental model of fracture healing provided a good surrogate for studying healing during the early time period as the callus stiffness is increasing as well as when diagnostic monitoring of the healing process is most critical. Based upon the data reported herein, the direct electromagnetic coupling method holds strong potential for clinical assessments and predictions of fracture healing. \u00a9 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. 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