{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T14:56:26Z","timestamp":1769093786763,"version":"3.49.0"},"reference-count":42,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T00:00:00Z","timestamp":1556064000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Distal radius fractures (DRFs) occur in various complexity patterns among patients differing in age, gender, and bone mineral density (BMD). Our aim was to investigate the association of patient characteristics, BMD, bone microarchitecture, and bone strength with the pattern complexity of DRFs. In this study, 251 patients aged 50\u201390 years with a radiologically confirmed DRF who attended the Fracture Liaison Service of VieCuri Medical Centre, the Netherlands, between November 2013 and June 2016 were included. In all patients fracture risk factors and underling metabolic disorders were evaluated and BMD measurement with vertebral fractures assessment by dual\u2010energy X\u2010ray absorptiometry was performed. Radiographs of all DRFs were reviewed by two independent investigators to assess fracture pattern complexity according to the AO\/OTA classification in extra\u2010articular (A), partially articular (B), and complete articular (C) fractures. For this study, patients with A and C fractures were compared. Seventy\u2010one patients were additionally assessed by high\u2010resolution peripheral quantitative computed tomography. Compared to group A, mean age, the proportion of males, and current smokers were higher in group C, but BMD and prevalent vertebral fractures were not different. In univariate analyses, age, male gender, trabecular area, volumetric BMD (vBMD), and stiffness were associated with type C fractures. In multivariate analyses, only male gender (odds ratio (OR) 8.48 95% confidence interval (CI) 1.75\u201341.18, <jats:italic>p<\/jats:italic>\u2009=\u20090.008]) and age (OR 1.11 [95% CI 1.03\u20131.19, <jats:italic>p<\/jats:italic>\u2009=\u20090.007]) were significantly associated with DRF pattern complexity. In conclusion, our data demonstrate that age and gender, but not body mass index, BMD, bone microarchitecture, or strength were associated with pattern complexity of DRFs.\u00a9 2019 The Authors. <jats:italic>Journal of Orthopaedic Research<\/jats:italic>\u00ae Published by Wiley Periodicals, Inc. J Orthop Res 37:1690\u20131697, 2019<\/jats:p>","DOI":"10.1002\/jor.24306","type":"journal-article","created":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T12:51:07Z","timestamp":1555073467000},"page":"1690-1697","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Bone Microarchitecture and Distal Radius Fracture Pattern Complexity"],"prefix":"10.1002","volume":"37","author":[{"given":"Anne M.","family":"Daniels","sequence":"first","affiliation":[{"name":"Department of Surgery VieCuri Medical Centre Venlo The Netherlands"},{"name":"NUTRIM School for Nutrition and Translational Research in Metabolism Maastricht University Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luuk M. 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