{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T03:14:35Z","timestamp":1769829275688,"version":"3.49.0"},"reference-count":51,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T00:00:00Z","timestamp":1575244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008220","name":"Bracco Imaging","doi-asserted-by":"publisher","award":["512924"],"award-info":[{"award-number":["512924"]}],"id":[{"id":"10.13039\/501100008220","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Supraspinatus (SSP) tendon tears represent a common indication for shoulder surgery. Yet, prediction of postoperative function and tendon retear remains challenging and primarily relies on morphologic magnetic resonance imaging (MRI)\u2010based parameters, supported by patients' demographic data like age, gender, and comorbidities. Considering continuously high retear rates, especially in patients with larger tears and negative prognostic factors, improved outcome prediction could be of high clinical value. Contrast\u2010enhanced ultrasound (CEUS) enables an assessment of dynamic perfusion of the SSP muscle. As a potential surrogate for muscle vitality, CEUS might reflect functional properties of the SSP and support improved outcome prediction after tendon repair. Fifty patients with isolated SSP tendon tears were prospectively enrolled. Preoperatively, SSP muscle perfusion was quantified by CEUS and conventional morphologic parameters like tear size, fatty infiltration, and tendon retraction were assessed by MRI. At six months follow\u2010up, shoulder function, tendon integrity, and muscle perfusion were reassessed. The predictive value of preoperative CEUS for postoperative shoulder function and tendon integrity was evaluated. 35 patients entered the statistical analysis. Preoperative CEUS\u2010based assessment of SSP perfusion significantly correlated with early postoperative shoulder function (Constant, <jats:italic>r<\/jats:italic>\u2009=\u20090.48, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.018) and tendon retear (<jats:italic>r<\/jats:italic>\u2009=\u20090.67, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). CEUS\u2010based subgroup analysis identified patients with exceptionally high, respectively low risk for tendon retear. CEUS\u2010based assessment of the SSP seemed to predict early shoulder function and tendon retear after SSP repair and allowed to identify patient subgroups with exceptionally high or low risk for tendon retear. \u00a9 2019 The Authors. <jats:italic>Journal of Orthopaedic Research<\/jats:italic>\u00ae published by Wiley Periodicals, Inc. on behalf of Orthopaedic Research Society. J Orthop Res 38:1150\u20101158, 2020<\/jats:p>","DOI":"10.1002\/jor.24535","type":"journal-article","created":{"date-parts":[[2019,11,26]],"date-time":"2019-11-26T11:50:50Z","timestamp":1574769050000},"page":"1150-1158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Contrast\u2010Enhanced Ultrasound (CEUS) as Predictor for Early Retear and Functional Outcome After Supraspinatus Tendon Repair"],"prefix":"10.1002","volume":"38","author":[{"given":"Pierre","family":"Kunz","sequence":"first","affiliation":[{"name":"Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Ultrasound Center, HTRG\u2014Heidelberg Trauma Research Group Heidelberg University Hospital  Schlierbacher Landstra\u00dfe 200a 69118 Heidelberg Germany"},{"name":"Clinic for Shoulder and Elbow Surgery Catholic Hospital Mainz  An der Goldgrube 11 55131 Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Mick","sequence":"additional","affiliation":[{"name":"Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Ultrasound Center, HTRG\u2014Heidelberg Trauma Research Group Heidelberg University Hospital  Schlierbacher Landstra\u00dfe 200a 69118 Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sascha","family":"Gross","sequence":"additional","affiliation":[{"name":"Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Ultrasound Center, HTRG\u2014Heidelberg Trauma Research Group Heidelberg University Hospital  Schlierbacher Landstra\u00dfe 200a 69118 Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Schmidmaier","sequence":"additional","affiliation":[{"name":"Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Ultrasound Center, HTRG\u2014Heidelberg Trauma Research Group Heidelberg University Hospital  Schlierbacher Landstra\u00dfe 200a 69118 Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Felix","family":"Zeifang","sequence":"additional","affiliation":[{"name":"Ethianum Klinik Heidelberg  Vo\u00dfstra\u00dfe 6 69115 Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc\u2010Andr\u00e9","family":"Weber","sequence":"additional","affiliation":[{"name":"Institute of Diagnostic and Interventional Radiology University Medical Center Rostock  Ernst\u2010Heydemann\u2010Stra\u00dfe 6 18057 Rostock Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3865-0610","authenticated-orcid":false,"given":"Christian","family":"Fischer","sequence":"additional","affiliation":[{"name":"Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Ultrasound Center, HTRG\u2014Heidelberg Trauma Research Group Heidelberg University Hospital  Schlierbacher Landstra\u00dfe 200a 69118 Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,2]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jor.2013.01.008"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp0800814"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-201106000-00007"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2013.10.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.N.01051"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.M.00583"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514529644"},{"key":"e_1_2_7_9_1","first-page":"78","article-title":"Fatty muscle degeneration in cuff ruptures. 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