{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T21:21:23Z","timestamp":1777324883632,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Previous studies have established that up to 1 year post total hip arthroplasty (THA), patients do not recover normal function and the magnitude of hip joint loading remains reduced compared to healthy individuals. However, the temporal nature of the loading profile has not been considered to identify individuals who are at a greater risk of poor functional outcomes following THA. This study aimed to determine changes to the profile and magnitude of the resultant hip joint reaction force before and up to 6 months post\u2010primary THA, and factors associated with atypical loading profiles. Hip joint loading was computed using a personalized lower\u2010limb musculoskeletal model in 43 participants awaiting primary THA for osteoarthritis (mean age: SD\u2009=\u200965, 14 years; body mass index: SD\u2009=\u200930, 5\u2009kg\/m<jats:sup>2<\/jats:sup>) before and up to 6 months after THA. Atypical, single\u2010peak loading profiles were observed for 11 patients before surgery, where four showed a single peak at 6 months. Patients displaying a single\u2010peak profile walked slower (mean difference: \u22120.4\u2009m\/s) compared to individuals displaying double\u2010peak profile (<jats:italic>P<\/jats:italic>\u2009=\u2009&lt;.001) and had significantly reduced sagittal plane hip range of motion during gait (mean difference \u22129.6\u00b0, <jats:italic>P<\/jats:italic>\u2009=\u2009&lt;.001). Self\u2010reported pain, function, and stiffness did not differentiate between patients with a single or double\u2010peak loading profile. Individuals with a single\u2010peak force profile did not meet the minimal clinically important hip range of motion during gait and would be classified as low\u2010functioning THA patients. Clinical Relevance: The temporal nature of the force profile may help to identify individuals who are at the greatest risk of poor functional outcomes after THA.<\/jats:p>","DOI":"10.1002\/jor.24716","type":"journal-article","created":{"date-parts":[[2020,5,13]],"date-time":"2020-05-13T14:59:12Z","timestamp":1589381952000},"page":"1550-1558","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Lower functioning patients demonstrate atypical hip joint loading before and following total hip arthroplasty for osteoarthritis"],"prefix":"10.1002","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3267-0098","authenticated-orcid":false,"given":"Jasvir S.","family":"Bahl","sequence":"first","affiliation":[{"name":"Alliance for Research in Exercise, Nutrition and Activity (ARENA), Allied Health &amp; Human Performance University of South Australia Adelaide 5000 Australia"},{"name":"Centre for Orthopaedic and Trauma Research, Discipline of Orthopaedics and Trauma University of Adelaide Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1158-8917","authenticated-orcid":false,"given":"John B.","family":"Arnold","sequence":"additional","affiliation":[{"name":"Alliance for Research in Exercise, Nutrition and Activity (ARENA), Allied Health &amp; Human Performance University of South Australia Adelaide 5000 Australia"},{"name":"IIMPACT in Health, Allied Health &amp; Human Performance University of South Australia Adelaide 5000 Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7842-6472","authenticated-orcid":false,"given":"Mark","family":"Taylor","sequence":"additional","affiliation":[{"name":"The Medical Device Research Institute, College of Science and Engineering Flinders University Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6254-2372","authenticated-orcid":false,"given":"Lucian B.","family":"Solomon","sequence":"additional","affiliation":[{"name":"IIMPACT in Health, Allied Health &amp; Human Performance University of South Australia Adelaide 5000 Australia"},{"name":"Department of Orthopaedics and Trauma Royal Adelaide Hospital Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6614-8663","authenticated-orcid":false,"given":"Dominic","family":"Thewlis","sequence":"additional","affiliation":[{"name":"Centre for Orthopaedic and Trauma Research, Discipline of Orthopaedics and Trauma University of Adelaide Adelaide South Australia Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,29]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Karrholm J Mohaddes M Odin D et al.Swedish Hip Arthroplasty Register Annual Report. 2017."},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2018.02.897"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2007.05.020"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2014.11.004"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2014.06.005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2018.01.002"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2009.03.037"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2015.02.014"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(01)00040-9"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-68237-0_2"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(01)00119-X"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2019.01.016"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2015.11.009"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1123\/jab.2016-0282"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2019.01.031"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/10255842.2018.1550577"},{"key":"e_1_2_9_18_1","first-page":"1833","article-title":"Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee","volume":"15","author":"Bellamy N","year":"1988","journal-title":"J Rheumatol"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.16.4.494"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.04.004"},{"key":"e_1_2_9_21_1","series-title":"Lecture Notes in Computer Science","volume-title":"Biomedical Simulation. ISBMS 2014","author":"Zhang J","year":"2014"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1109\/10.102791"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2017.09.012"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.piutam.2011.04.021"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155612"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13029-015-0044-4"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(74)90056-6"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(01)00140-0"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22996"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/10255842.2016.1181174"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2483"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9290(00)00096-8"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2009.05.014"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1191\/0269215506cr958oa"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2008.07.001"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/ket180"},{"key":"e_1_2_9_37_1","unstructured":"WardSR SmallwoodLH LieberRL.Scaling of human lower extremity muscle architecture to skeletal dimensions. In: ISB XXth Congress \u2010 ASB 29th Annual Meeting Cleveland OH;2005."},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(99)00033-8"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fjor.24716","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.24716","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jor.24716","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.24716","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,6]],"date-time":"2023-09-06T11:22:48Z","timestamp":1693999368000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.24716"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,29]]},"references-count":37,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["10.1002\/jor.24716"],"URL":"https:\/\/doi.org\/10.1002\/jor.24716","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,29]]},"assertion":[{"value":"2019-12-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-01","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}