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Reaming prior to locked intramedullary nailing is a frequently used technique to stabilize femoral diaphysis fractures. However, in polytraumatized patients, complications such as fat emboli and acute respiratory distress syndrome have\u00a0been associated with reaming. The reaming irrigator aspirator (RIA) system provides concomitant irrigation and suction of the intramedullary contents, and should, therefore, reduce reaming\u2010associated complications. The aim of the study was to investigate cardiac function after multiple trauma with regard to two different RIA devices (RIAI vs RIAII). 15 male pigs were included in the study. Pigs received either sham treatment or multiple trauma (chest trauma, femur fracture, liver laceration, and hemorrhagic shock), followed by intramedullary nailing after reaming with either the RIAI or RIAII system (RIAII: reduced diameter of the reamer, improved control of irrigation and suction). Cardiac function was assessed by transesophageal echocardiography and systemic inflammation as well as local cardiac damage examined. Pigs of both treatment groups\u00a0showed impaired cardiac function, valvular insufficiency, and cardiac damage. Systemic inflammation and local cardiac alterations were observed which might contribute to early myocardial damage in vivo. Multiple trauma including long\u2010bone fracture and subsequent intramedullary reaming induces cardiac dysfunction and valvular insufficiency, which might be linked to both mechanical cardiac injury and increased systemic inflammation. 6\u2009hours after trauma there are less differences between RIAI and RIAII treatment with regard to post\u2010traumatic cardiac consequences in multiple injured pigs, indicating no beneficial effect of RIAII over RIAI.<\/jats:p>","DOI":"10.1002\/jor.24830","type":"journal-article","created":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T14:12:33Z","timestamp":1598105553000},"page":"2608-2618","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma"],"prefix":"10.1002","volume":"38","author":[{"given":"Ina","family":"Lackner","sequence":"first","affiliation":[{"name":"Department of Traumatology, Hand\u2010, Plastic\u2010 and Reconstructive Surgery University Hospital Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birte","family":"Weber","sequence":"additional","affiliation":[{"name":"Department of Traumatology, Hand\u2010, Plastic\u2010 and Reconstructive Surgery University Hospital Ulm  Ulm Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theodore","family":"Miclau","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Orthopaedic Trauma Institute University of California  San Francisco California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nina","family":"Holzwarth","sequence":"additional","affiliation":[{"name":"Department of Traumatology, Hand\u2010, Plastic\u2010 and Reconstructive Surgery University 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