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For this reason, the field has shifted gradually towards suture repair, with the intent of preservation of the tissue. \u201cSave the Meniscus\u201d is now a prolific theme in the field; however, meniscal repair can be challenging and ineffective in many scenarios. The objectives of this review are to present the current state of surgical management of meniscal injuries and to explore current approaches being developed to enhance meniscal repair. Through a systematic literature review, we identified meniscal tear classifications and prevalence, approaches being used to improve meniscal repair, and biological\u2010 and material\u2010based systems being developed to promote meniscal healing. We found that biologic augmentation typically aims to improve cellular incorporation to the wound site, vascularization in the inner zones, matrix deposition, and inflammatory relief. Furthermore, materials can be used, both with and without contained biologics, to further support matrix deposition and tear integration, and novel tissue adhesives may provide the mechanical integrity that the meniscus requires. Altogether, evaluation of these approaches in relevant in vitro and in vivo models provides new insights into the mechanisms needed to salvage meniscal tissue, and along with regulatory considerations, may justify translation to the clinic. With the need to restore long\u2010term function to injured menisci, biologists, engineers, and clinicians are developing novel approaches to enhance the future of robust and consistent meniscal reparative techniques.<\/jats:p>","DOI":"10.1002\/jor.25021","type":"journal-article","created":{"date-parts":[[2021,3,10]],"date-time":"2021-03-10T06:11:12Z","timestamp":1615356672000},"page":"1368-1382","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":147,"title":["Meniscal repair: The current state and recent advances in augmentation"],"prefix":"10.1002","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7080-1311","authenticated-orcid":false,"given":"Sonia","family":"Bansal","sequence":"first","affiliation":[{"name":"University of Pennsylvania  Philadelphia Pennsylvania 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