{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:43:27Z","timestamp":1783529007757,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,9,13]],"date-time":"2022-09-13T00:00:00Z","timestamp":1663027200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2020YFS0075"],"award-info":[{"award-number":["2020YFS0075"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To compare the differences among constructs with one\u2010level cervical disc arthroplasty (CDA) and two\u2010level anterior cervical discectomy and fusion (ACDF).\u00a0A retrospective study was conducted involving patients who underwent one\u2010level CDA and two\u2010level ACDF between June 2012 and July 2020. According to the different locations of CDA and ACDF, we divided the constructs into three types: type \u2160a: CDA\u2010ACDF\u2010ACDF; type \u2160b: ACDF\u2010CDA\u2010ACDF; type \u2160c: ACDF\u2010ACDF\u2010CDA. The differences of clinical and radiological outcomes were evaluated.\u00a0Fifty\u2010three patients were included with 29 in type \u2160a group, 11 in type \u2160b group, and 13 in type \u2160c group. After surgery, all groups showed significant improvement in apanese Orthopedic Association, Neck Disability Index, and Visual Analog Scale scores (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Range of motion\u00a0(ROM) of the total cervical spine in type \u2160c group decreased significantly compared with those in type \u2160a and type \u2160b groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). No significant differences in ROM of the arthroplasty segment and the variations in ROM of the superior adjacent segment were observed among the\u00a0three groups. The fusion rates of the superior ACDF segments were significantly higher at 6 and 12 months postoperatively than those of the inferior ACDF segments (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).\u00a0The clinical outcomes were similar among constructs concerning different locations of CDA and ACDF in three\u2010level hybrid surgery. ROM of the cervical spine in type \u2160c group decreased significantly compared with that in type \u2160a and type \u2160b groups. The fusion rates of superior ACDF segments were higher at early time points after surgery than those of inferior ACDF segments.<\/jats:p>","DOI":"10.1002\/jor.25436","type":"journal-article","created":{"date-parts":[[2022,9,5]],"date-time":"2022-09-05T00:59:01Z","timestamp":1662339541000},"page":"1105-1114","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Cervical disc arthroplasty combined with two\u2010level ACDF for the treatment of contiguous three\u2010level cervical degenerative disc disease: A comparative study"],"prefix":"10.1002","volume":"41","author":[{"given":"Kangkang","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Orthopedics, West China Hospital Sichuan University  Chengdu Sichuan 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