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Pain is a hallmark presentation of OA. Topical nonsteroidal anti\u2010inflammatory drugs (NSAIDs) are recommended by many international guidelines as an early treatment option of the management of osteoarthritic pain. However, the use of topical NSAIDs remains low in Malaysia and appears not to be a preferred agent in managing OA pain by prescribers. There is also limited guidance from local medical bodies on the use of topical NSAIDs to manage OA pain. This consensus recommendation is intended to serve as a practical guide for healthcare practitioners on the use of topical NSAIDs in the management of OA pain. Eight statements and recommendations were finalized covering the areas of OA burden, topical NSAIDs formulations, safety and efficacy of topical NSAIDs, and patient education. Robust evidence is available to support the efficacy and safety of topical NSAIDs, with its benefits further strengthened by ease of use and access. Taking these into consideration, we recommend that healthcare practitioners advocate for the early use of topical NSAIDs over oral NSAIDs for mild\u2010to\u2010moderate OA pain, while engaging in a shared decision\u2010making process with patients for optimal clinical outcomes.<\/jats:p>","DOI":"10.1002\/jor.25549","type":"journal-article","created":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T07:17:08Z","timestamp":1678951028000},"page":"1916-1924","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Topical nonsteroidal anti\u2010inflammatory drugs for management of osteoarthritis pain: A consensus recommendation"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4215-1689","authenticated-orcid":false,"given":"Joon\u2010Kiong","family":"Lee","sequence":"first","affiliation":[{"name":"Beacon Hospital Petaling Jaya Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azlina A.","family":"Abbas","sequence":"additional","affiliation":[{"name":"National Orthopaedic Centre of Excellence for Research and Learning (NOCERAL) Universiti Malaya Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tien\u2010Eang","family":"Cheah","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Pantai Hospital Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruslan Nazaruddin","family":"Simanjuntak","sequence":"additional","affiliation":[{"name":"ALTY Hospital Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sargunan","family":"Sockalingam","sequence":"additional","affiliation":[{"name":"Rheumatology Unit Universiti Malaya Medical Centre Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2068-4238","authenticated-orcid":false,"given":"Sharifah","family":"Roohi","sequence":"additional","affiliation":[{"name":"Hand &amp; Upper Limb Centre Pantai Hospital Kuala Lumpur Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60692-4"},{"key":"e_1_2_8_3_1","unstructured":"Global Burden of Disease Collaborative Network.Global Burden of Disease Study 2019 (GBD 2019) results. 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