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However, its effects on muscle atrophy are poorly understood. We evaluated the effects of whole\u2010body vibration on denervated skeletal muscle atrophy. Whole\u2010body vibration was performed on rats from Day 15 to 28 after denervation injury. Motor performance was evaluated using an inclined\u2010plane test. Compound muscle action potentials of the tibial nerve were examined. Muscle wet weight and muscle fiber cross\u2010sectional area were measured. Myosin heavy chain isoforms were analyzed in both muscle homogenates and single myofibers. Whole\u2010body vibration resulted in a significantly decreased inclination angle and muscle weight, but not muscle fiber cross\u2010sectional area of fast\u2010twitch gastrocnemius compared to denervation only. In denervated gastrocnemius, a fast\u2010to\u2010slow shift was observed in myosin heavy chain isoform composition following whole\u2010body vibration. There were no significant changes in muscle weight, muscle fiber cross\u2010sectional area, and myosin heavy chain isoform composition in denervated slow\u2010twitch soleus. These results imply that whole\u2010body vibration does not promote recovery of denervation\u2010induced muscle atrophy.<\/jats:p>","DOI":"10.1002\/jor.25589","type":"journal-article","created":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T08:39:40Z","timestamp":1683103180000},"page":"2579-2587","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impacts of whole\u2010body vibration on denervated skeletal\u2010muscle atrophy in rats"],"prefix":"10.1002","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8119-4297","authenticated-orcid":false,"given":"Eun Sil","family":"Koh","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Medicine National Medical Center Seoul Republic of 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