{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T06:43:43Z","timestamp":1775976223339,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T00:00:00Z","timestamp":1719273600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P30\u2010GM122732 (COBRE Bio\u2010engineering Core)"],"award-info":[{"award-number":["P30\u2010GM122732 (COBRE Bio\u2010engineering Core)"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The multidirectional biomechanics of the thumb carpometacarpal (CMC) joint underlie the remarkable power and precision of the thumb. Because of the unconfined nature of thumb CMC articulation, these biomechanics are largely dictated by ligaments, notably the anterior oblique ligament (AOL) and the dorsoradial ligament (DRL). However, the rotational and translational stabilizing roles of these ligaments remain unclear, as evidenced by the variety of interventions employed to treat altered pathological CMC biomechanics. The purpose of this study was to determine the effects of sectioning the AOL (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20098) or DRL (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u20098) on thumb CMC joint biomechanics (rotational range\u2010of\u2010motion [ROM] and stiffness, translational ROM) in 26 rotational directions, including internal and external rotation, and in eight translational directions. Using a robotic musculoskeletal simulation system, the first metacarpal of each specimen (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200916) was rotated and translated with respect to the trapezium to determine biomechanics before and after ligament sectioning. We observed the greatest increase in rotational ROM and decrease in rotational stiffness in flexion directions and internal rotation following DRL transection and in extension directions following AOL transection. The greatest increase in translational ROM was in dorsal and radial directions following DRL transection and in volar directions following AOL transection. These data suggest the AOL and DRL play complementary stabilizing roles, primarily restraining translations in the direction of and rotations away from the ligament insertion sites. These findings may inform future interventions or implant designs for pathological CMC joints.\n                  <\/jats:p>","DOI":"10.1002\/jor.25922","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T11:54:52Z","timestamp":1719316492000},"page":"2390-2399","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The multidirectional roles of the anterior oblique ligament and dorsoradial ligament of the thumb carpometacarpal joint"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5811-1112","authenticated-orcid":false,"given":"Josephine M.","family":"Kalshoven","sequence":"first","affiliation":[{"name":"Institute for Biology, Engineering, and Medicine Brown University Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rohit","family":"Badida","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory, Department of Orthopedics The Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4513-1699","authenticated-orcid":false,"given":"Amy M.","family":"Morton","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory, Department of Orthopedics The Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janine","family":"Molino","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory, Department of Orthopedics The Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence Rhode Island USA"},{"name":"Lifespan Biostatistics, Epidemiology, Research Design and Informatics Core Rhode Island Hospital Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnold\u2010Peter C.","family":"Weiss","sequence":"additional","affiliation":[{"name":"Bioengineering Laboratory, Department of Orthopedics The Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy L.","family":"Ladd","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Robert A. Chase Hand &amp; Upper Limb Center Stanford University School of Medicine Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph J.","family":"Crisco","sequence":"additional","affiliation":[{"name":"Institute for Biology, Engineering, and Medicine Brown University Providence Rhode Island USA"},{"name":"Bioengineering Laboratory, Department of Orthopedics The Warren Alpert Medical School of Brown University and Rhode Island Hospital Providence Rhode Island USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,6,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.38B4.902"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-013-3063-y"},{"key":"e_1_2_7_4_1","first-page":"165","article-title":"The thumb carpometacarpal joint: anatomy, hormones, and biomechanics","volume":"62","author":"Ladd 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