{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T10:33:11Z","timestamp":1768645991203,"version":"3.49.0"},"reference-count":35,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Large acetabular bone defects are challenging in hip revision surgery. Clinical assessment is crucial to evaluate modern technologies in surgical reconstruction. We aimed to better understand the bone remodeling that occurs following acetabular reconstruction. Our objectives were: (1) To characterize changes in the shape of the pelvis by studying sequential computed tomography (CT) scans collected immediately and 1\u2010year postoperatively and (2) to identify which part of the pelvis is most susceptible to remodeling. We used the CT scans taken at two timepoints, of 24 patients with acetabular bone defects classified as Paprosky IIIB, treated with three\u2010dimensional (3D)\u2010printed custom\u2010made acetabular implants. Segmented 3D models of the bony pelvis were co\u2010registered using three different techniques. A global co\u2010registration of the full pelvis was conducted, followed by the co\u2010registration of the innominate bone and then ilium only, on the ipsilateral reconstructed side. The relative movements of the ilium, ischium, and pubis were analyzed from visual inspection and using co\u2010registration metrics (root mean square error and intersection over union). No bone remodeling was found in 14\/24 patients (58%). The co\u2010registration of the innominate bone indicated bone remodeling in five cases (21%), while the remaining five cases (21%) presented remodeling in the global co\u2010registration but not the innominate bone co\u2010registration, suggestive of changes occurring at the sacroiliac joint. Changes in the pelvic shape were greatest at the pubis and ischium. Bone remodeling may occur in complex cases of Paprosky type IIIB defects, after acetabular reconstruction (occurrence of 21%, 5\/24 cases). Surgeons and engineers should consider this when monitoring implant migration.<\/jats:p>","DOI":"10.1002\/jor.25936","type":"journal-article","created":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T03:20:52Z","timestamp":1720754452000},"page":"2784-2795","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Bone remodeling after revision total hip arthroplasty for large acetabular defects"],"prefix":"10.1002","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7396-4068","authenticated-orcid":false,"given":"Angelika","family":"Ramesh","sequence":"first","affiliation":[{"name":"Department of Mechanical Engineering University College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Di Laura","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering University College London London UK"},{"name":"Royal National Orthopaedic Hospital NHS Trust Stanmore UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2721-7694","authenticated-orcid":false,"given":"Sara","family":"De Angelis","sequence":"additional","affiliation":[{"name":"Department of Mechanical Engineering University College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johann","family":"Henckel","sequence":"additional","affiliation":[{"name":"Royal National Orthopaedic Hospital NHS Trust Stanmore UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alister","family":"Hart","sequence":"additional","affiliation":[{"name":"Royal National Orthopaedic Hospital NHS Trust Stanmore UK"},{"name":"Institute of Orthopaedics and Musculoskeletal Science, University College London London UK"},{"name":"Cleveland Clinic London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.99B5.BJJ-2014-0264.R3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.97B6.35129"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.5301\/hipint.5000246"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/17453674.2020.1819729"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.91B7.22181"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV15I8A118"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2008.07.014"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/17453674.2021.1906082"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2022.02.060"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-010-1239-4"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12891-021-04161-4"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-018-4203-5"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1120700018813208"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arth.2006.05.015"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.OA.22.00120"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.25547"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41205-020-00074-5"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stlm.2023.100117"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matdes.2021.110024"},{"key":"e_1_2_8_21_1","first-page":"1","article-title":"The role of bone remodeling in measuring migration of custom implants for large acetabular defects","author":"De Angelis S","year":"2024","journal-title":"J Orthop Res"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eswa.2022.116873"},{"key":"e_1_2_8_23_1","volume-title":"Medical Image Computing and Computer\u2010Assisted Intervention\u2013MICCAI 2012","author":"Ayache N","year":"2012"},{"key":"e_1_2_8_24_1","unstructured":"Flitwick Osteopathic Clinic.2021. 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