{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T13:45:16Z","timestamp":1792590316692,"version":"4.5.0"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T00:00:00Z","timestamp":1732147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007371","name":"Svend Andersen Fonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007371","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Guided growth for correction of rotational deformities has been reported in several preclinical and clinical studies. Different adverse effects, like growth retardation, articular deformities, and rebound effect have been reported. We have tested a novel plate concept (RotOs Plate<jats:sup>TM<\/jats:sup>) intended for the correction of rotational deformities of long bones by guided growth in a porcine model. The plate has sliding screw holes intended to allow for longitudinal growth. Fourteen skeletally immature female pigs were included in the study in a paired design. Mean duration of intervention was 88 days (83\u201398). CTscans and X\u2010rays were performed at plate insertion and removal. From the CTscans, 3D\u2010models of the left and right femora were made and used for measuring the achieved rotation. Three pigs were excluded for reasons not related to the plate design. The plates rotated as intended in all pigs. In two pigs, there was a cut\u2010out of the proximal screw on the lateral side. Data from these two pigs were included in the results. We observed a mean difference in rotation between the left and right femur of 5.7\u00b0 in the external direction (CI: 3.7\u00b0\u22127.7\u00b0). No statistically significant deformities in the coronal and sagittal plane were observed. The plate worked as intended, that is, the intended rotation was achieved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Clinical Significance<\/jats:title><jats:p>This large animal study shows promising results for the feasibility of the method. It is an important first step in validating the technique and detecting possible adverse effects before clinical studies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jor.26019","type":"journal-article","created":{"date-parts":[[2024,11,21]],"date-time":"2024-11-21T10:47:07Z","timestamp":1732186027000},"page":"617-621","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A novel plate design for rotational guided growth: An experimental study in immature porcine femurs"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-4867-3219","authenticated-orcid":false,"given":"Ahmed","family":"Halloum","sequence":"first","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Rahbek","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shima","family":"Gholinezhad","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Materials and Production Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Kold","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Materials and Production Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Duedal","family":"R\u00f6lfing","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Tirta","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Arildsen","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed A.","family":"Abood","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopaedics Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Orthopaedics Aarhus University Hospital Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1530\/EOR-23-0149"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.L.00819"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2016.1152450"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000001106"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/jllr.jllr_6_18"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2019.06.005"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000001004"},{"issue":"4","key":"e_1_2_8_9_1","article-title":"An innovative plate concept for rotational guided growth: a porcine pilot study","volume":"16","author":"Abood AA","year":"2024","journal-title":"Cureus"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11517-006-0104-7"},{"key":"e_1_2_8_11_1","unstructured":"Dawson\u2010HaggertyM.trimesh. Version 3.2.0;2019.https:\/\/trimesh.org\/"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jeo2.12111"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3390\/children10010070"},{"issue":"9","key":"e_1_2_8_14_1","article-title":"Three\u2010dimensional analysis versus two\u2010dimensional slice\u2010based analysis of CT for measuring femoral torsion and its correlation to passive hip range of motion","volume":"14","author":"Ratner D","year":"2022","journal-title":"Cureus"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.26019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,11]],"date-time":"2025-02-11T05:23:52Z","timestamp":1739251432000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.26019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,21]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/jor.26019"],"URL":"https:\/\/doi.org\/10.1002\/jor.26019","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,21]]},"assertion":[{"value":"2024-07-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}