{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T22:26:21Z","timestamp":1757629581292,"version":"3.44.0"},"reference-count":29,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T00:00:00Z","timestamp":1753574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["952150"],"award-info":[{"award-number":["952150"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:label\/><jats:p>Metal plates are commonly used for the fixation of metacarpal fractures, but are associated with complications such as tendon adhesions that impair finger mobility. AdhFix, a novel osteosynthesis material, may reduce these complications, but its biomechanical performance in the metacarpal region remains untested. This study aimed to evaluate internal bending moments during postoperative rehabilitation and assess the biomechanical potential of AdhFix in treating comminuted metacarpal shaft fractures using a human cadaveric model. In five cadaveric hands, unstable shaft fractures of the second, third, and fourth metacarpals were simulated using a 3\u2009mm osteotomy gap and stabilized with polyether ether ketone (PEEK) plates and stainless\u2010steel cortical screws. A custom 3D\u2010printed guide ensured accurate osteotomy and screw positioning. Tendon loading was simulated by pulling flexor digitorum profundus tendons until fingertip\u2010to\u2010palm contact was achieved, followed by wrist flexion using 100\u2009N of force on the flexor carpi radialis and ulnaris tendons. Bending of the fixation was captured using stereographic imaging, and internal bending moments were calculated via finite element modeling. After removal of the PEEK plate, the procedure was repeated using AdhFix for fixation. Maximum internal bending moments were 6.14\u2009\u00b1\u20092.03\u2009Nmm during finger flexion and 3.37\u2009\u00b1\u20091.64\u2009Nmm during wrist flexion. AdhFix demonstrated mechanical integrity under both conditions with no observed failure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Statement of Clinical Significance<\/jats:title><jats:p>AdhFix may provide a mechanically stable alternative to conventional plates during early rehabilitation, potentially reducing tendon adhesions and preserving finger mobility.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jor.70027","type":"journal-article","created":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T09:20:55Z","timestamp":1753608055000},"page":"1787-1795","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Biomechanical Characterization of Metacarpal Fixation: Internal Load Determination and Evaluation of a Novel Adhesive 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