{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:33:47Z","timestamp":1792456427322,"version":"4.5.0"},"reference-count":63,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T00:00:00Z","timestamp":1757462400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005860","name":"Helsefonden","doi-asserted-by":"publisher","award":["22\u2010B\u20100152."],"award-info":[{"award-number":["22\u2010B\u20100152."]}],"id":[{"id":"10.13039\/501100005860","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Functional recovery after total knee arthroplasty (TKA) varies widely among individuals, and traditional assessments often fail to detect subtle changes in real\u2010world walking ability. Wearable sensors offer continuous and objective tracking of gait outside of clinical settings. In this prospective, longitudinal study, thirty\u2010one patients undergoing unilateral TKA wore thigh\u2010mounted accelerometers continuously from 2 weeks before surgery through 90 days postoperatively. We analyzed temporal gait features (stride time and duty factor) and frequency\u2010domain metrics (power of the first five frequencies of triaxial acceleration), along with weekly EQ\u20105D\u20103L index scores (a summary measure of health\u2010related quality of life) and visual analog scale (VAS) ratings (patient's self\u2010reported health on a 0\u2013100 scale). Gait acceleration profiles demonstrated significant postoperative disruptions, particularly during mid\u2010stance and terminal swing, followed by gradual normalization, approaching baseline by day 90. Gait temporal parameters also exhibited transient alterations and recovery trends. Using LASSO logistic regression, Fourier\u2010derived gait features discriminated responders and non\u2010responders based on improvements in EQ\u20105D\u20103L outcomes above the minimal clinically important difference (AUC: 0.80\u20130.81). Specific harmonic changes across the vertical, mediolateral, and anteroposterior axes were significantly associated with the perceived health gains. The results indicated that frequency\u2010based gait metrics from wearable sensors are sensitive digital biomarkers for short\u2010term functional improvements.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jor.70058","type":"journal-article","created":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T03:16:27Z","timestamp":1757560587000},"page":"2165-2177","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Monitoring Gait Recovery After Total Knee Arthroplasty Using Wearable Sensors: Responsiveness of Gait Accelerations"],"prefix":"10.1002","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6901-0763","authenticated-orcid":false,"given":"Arash","family":"Ghaffari","sequence":"first","affiliation":[{"name":"Interdisciplinary Orthopedics, Department of Orthopedics Surgery Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pernille Damborg","family":"Clasen","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopedics, Department of Orthopedics Surgery Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kappel","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopedics, Department of Orthopedics Surgery Aalborg University Hospital Aalborg Denmark"},{"name":"Department of Orthopedics Surgery Capio Private Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Rasmussen","sequence":"additional","affiliation":[{"name":"Department of Materials and Production Aalborg University Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reed D.","family":"Gurchiek","sequence":"additional","affiliation":[{"name":"Department of Bioengineering Clemson University Clemson South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00f8ren","family":"Kold","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopedics, Department of Orthopedics Surgery Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Rahbek","sequence":"additional","affiliation":[{"name":"Interdisciplinary Orthopedics, Department of Orthopedics Surgery Aalborg University Hospital Aalborg Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,10]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"1672","volume-title":"Knee Replacement","author":"Price A. 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