{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T20:53:11Z","timestamp":1787863991456,"version":"build-2784847793"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The study aimed to compare contact stresses for a novel lumbar total joint replacement (LTJR) during a standardized duty cycle with elevated loading conditions. A finite element model (FEM) of an LTJR was developed, verified, and validated using the ASME V&amp;V40 standard. Simulations were performed using LS\u2010Dyna. Increasing the axial loading for the 95th percentile male generally resulted in an increase in the peak contact pressures throughout the duty cycle. Specifically, contact pressure reached a maximum of 37.6\u2009MPa. Despite this increase, the polyethylene peak contact stresses remained considerably lower than values previously documented during impingement. For 95th percentile male loading, the bearing mechanics of the LTJR design remained reasonably consistent with the 50th male loading scenario. Contact between the superior and inferior components remained confined to the intended hemispherical bearing surfaces, without evidence of impingement. The contact stresses in elevated loading scenarios fell below the levels associated with impingement loading. The polyethylene bearing stresses indicate that relative risks of wear and surface damage, including pitting, delamination, and fracture associated with a 95th percentile male, will be lower relative to the conditions from impingement testing.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Clinical Significance:<\/jats:bold>\n                    Our in silico approach to exploring elevated boundary conditions for spine wear testing will facilitate future test method development.\n                  <\/jats:p>","DOI":"10.1002\/jor.70115","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T08:30:21Z","timestamp":1767342621000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["High Demand Loading Conditions and Their Effect on Polyethylene Stresses in Lumbar Total Joint Replacement: Implications for Spine Wear Protocols"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3885-500X","authenticated-orcid":false,"given":"Steven M.","family":"Kurtz","sequence":"first","affiliation":[{"name":"Implant Research Core, School of Biomedical Engineering, Science, and Health Systems Drexel University Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven A.","family":"Rundell","sequence":"additional","affiliation":[{"name":"Explico Inc. Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Spece","sequence":"additional","affiliation":[{"name":"Implant Research Core, School of Biomedical Engineering, Science, and Health Systems Drexel University Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1704-3360","authenticated-orcid":false,"given":"Ryan L.","family":"Siskey","sequence":"additional","affiliation":[{"name":"Exponent Inc., One uCity Square Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ron V.","family":"Yarbrough","sequence":"additional","affiliation":[{"name":"3Spine Inc. Chattanooga Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"ASTM International \u201cASTM F3295\u201018: Standard Guide for Impingement Testing of Total Disc Prostheses \u201d West Conshohocken PA USA 2018."},{"key":"e_1_2_7_3_1","unstructured":"ISO 18192\u20101:2018. Implants for Surgery\u2014Wear of Total Intervertebral Spinal Disc Prostheses\u2014Part 1: Loading and Displacement Parameters for Wear Testing and Corresponding Environmental Conditions for Test (ISO 2018)."},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.07.040"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.semss.2011.11.011"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-008-0840-5"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medengphy.2012.07.003"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2015.09.007"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2020.12.001"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.14444\/8746"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering10101198"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/bioengineering12030229"},{"key":"e_1_2_7_13_1","unstructured":"ASME V&V 40\u20102018. \u201cAssessing Credibility of Computational Modeling Through Verification and Validation: Application to Medical Devices \u201d (American Society of Mechanical Engineers 2018)."},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1201\/b16369"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2018.03.029"},{"key":"e_1_2_7_16_1","unstructured":"\u201cASTM F2423\u201005. Standard Guide for Functional Kinematic and Wear Assessment of Total Disc Prostheses \u201d (American Society for Testing and Materials 2005)."},{"issue":"46","key":"e_1_2_7_17_1","first-page":"44","article-title":"Anthropometric Reference Data for Children and Adults: United States, 2015\u20132018. National Center for Health Statistics","volume":"3","author":"Fryar C. D. C. M.","year":"2021","journal-title":"Vital and Health Statistics"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820170510"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1115\/1.3138543"},{"key":"e_1_2_7_20_1","first-page":"229","article-title":"The Effect of Metal Backing on Stresses in Polyethylene Acetabular Components","author":"Bartel D. L.","year":"1983","journal-title":"Hip"},{"key":"e_1_2_7_21_1","first-page":"1041","article-title":"The Effect of Conformity, Thickness, and Material on Stresses in Ultra\u2010High Molecular Weight Components for Total Joint Replacement","volume":"68","author":"Bartel D. L.","year":"1986","journal-title":"Journal of Bone & Joint Surgery"},{"key":"e_1_2_7_22_1","first-page":"76","article-title":"Stresses in Polyethylene Components of Contemporary Total Knee Replacements","volume":"317","author":"Bartel D. L.","year":"1995","journal-title":"Clinical Orthopaedics and Related Research"},{"key":"e_1_2_7_23_1","article-title":"Comparison of Daily Motion of the Cervical and Lumbar Spine to ASTM F2423\u201011 and ISO 18192\u20101.2011 Standard Testing","volume":"9","author":"Cobian D.","year":"2011","journal-title":"Journal of ASTM International"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/jsp2.70069"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.70115","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jor.70115","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.70115","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:57:18Z","timestamp":1769648238000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.70115"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/jor.70115"],"URL":"https:\/\/doi.org\/10.1002\/jor.70115","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70115"}}