{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T03:11:20Z","timestamp":1779333080920,"version":"3.51.4"},"reference-count":61,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,12]],"date-time":"2026-04-12T00:00:00Z","timestamp":1775952000000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008749","name":"American College of Sports Medicine","doi-asserted-by":"publisher","award":["22\u201001803"],"award-info":[{"award-number":["22\u201001803"]}],"id":[{"id":"10.13039\/100008749","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000980","name":"Arthritis Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000980","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Aberrant gait biomechanics following ACL reconstruction (ACLR) are linked to knee osteoarthritis development in adult patients. However, limited research exists to characterize walking biomechanics profiles of pediatric ACLR patients. The study purpose was to determine (1) differences in biomechanical profiles between pediatric ACLR patients (Tanner Stage I\u2013IV) and two comparison\u2010control groups (i.e., uninjured, matched pediatrics, adult\u2010matched ACLR); (2) associations between biomechanical and Knee Osteoarthritis Outcomes Score (KOOS)\u2010Child outcomes in pediatric ACLR patients. Gait biomechanics were collected in pediatric ACLR (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200925), pediatric controls (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200925), and adult ACLR groups (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200925). Pediatric patients completed the KOOS\u2010Child at the same session. A functional mixed effects model determined between\u2010group differences in biomechanical variables. Uncorrected partial correlations, controlling for gait speed, were utilized to determine the association between discrete biomechanics and KOOS\u2010Child scores. Pediatric ACLR patients demonstrated lesser first and second peak vertical ground reaction force (vGRF) and greater midstance vGRF than pediatric controls. Pediatric ACLR patients exhibited lesser midstance and greater late stance vGRF compared to the adult ACLR group. Pediatric ACLR patients demonstrated lesser knee flexion angle, knee extension moment, and knee abduction moment profiles compared to pediatric controls and adult ACLR patients throughout the majority of the stance phase. Greater midstance vGRF was associated with greater KOOS\u2010Child Quality of Life scores in the contralateral limb (\n                    <jats:italic>r<\/jats:italic>\n                    \u2009=\u20090.54,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.006). Pediatric ACLR patients exhibit unique biomechanical profiles compared to pediatric controls and adult ACLR patients; however, the associations with patient\u2010reported outcomes remain unclear. Pediatrics may experience an exaggerated response to ACLR that may impact knee joint health.\n                  <\/jats:p>","DOI":"10.1002\/jor.70196","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T04:11:29Z","timestamp":1776053489000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gait Biomechanical Profiles Following Anterior Cruciate Ligament Reconstruction in Sexually\u2010Immature Pediatrics"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8824-9366","authenticated-orcid":false,"given":"Elizabeth","family":"Bjornsen","sequence":"first","affiliation":[{"name":"Department of Kinesiology East Carolina University Greenville North Carolina USA"},{"name":"Human Movement Science Curriculum University of North Carolina at Chapel Hill Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. Troy","family":"Blackburn","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason R.","family":"Franz","sequence":"additional","affiliation":[{"name":"Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill and North Carolina State University Chapel Hill and Raleigh North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. Zachary","family":"Horton","sequence":"additional","affiliation":[{"name":"Department of Statistics University of California at Santa Cruz Santa Cruz California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darin","family":"Padua","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra","family":"Shultz","sequence":"additional","affiliation":[{"name":"Department of Kinesiology University of North Carolina at Greensboro Greensboro North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha","family":"Tayne","sequence":"additional","affiliation":[{"name":"Department of Orthopedics University of North Carolina at Chapel Hill, Chapel Hill  North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Pietrosimone","sequence":"additional","affiliation":[{"name":"Department of Exercise and Sport Science University of North Carolina at Chapel Hill Chapel Hill North Carolina USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2016\u20101877"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513518412"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0000000000000482"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465231185742"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10439\u2010014\u20101117\u20102"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515608475"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000002208"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546517749850"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40279\u2010016\u20100510\u20104"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.23534"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325967114552405"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/23259671211010772"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102015\u2010094797"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0268\u20100033(01)00097\u20103"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062\u20106050\u201052.6.06"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.23317"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000001776"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.24056"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/19476035211072220"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000001834"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.05.025"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.26001"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.4085\/1062-6050-0052.22"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325967119861803"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/9780470696255.ch1"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0000000000000391"},{"issue":"1","key":"e_1_2_8_28_1","first-page":"130","article-title":"Body Composition Analysis in the Pediatric Population","volume":"10","author":"Weber D. R.","year":"2012","journal-title":"Pediatric Endocrinology Reviews: PER"},{"key":"e_1_2_8_29_1","doi-asserted-by":"crossref","unstructured":"R. M.Malina C.Bouchard andO.Bar\u2010OrGrowth Maturation and Physical Activity. 2nd ed. Human Kinetics;2004.","DOI":"10.5040\/9781492596837"},{"key":"e_1_2_8_30_1","first-page":"117","article-title":"Growth and Endocrinology of the Adolescent","volume":"26","author":"Tanner J. M.","year":"1969","journal-title":"Endocrine and Genetic Disease of Childhood and Adolescence."},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02088471"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1067\/mpd.2002.125907"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajhb.1310060406"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1998.28.2.88"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107525\u20101\u201064"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.3109\/17453674.2012.747921"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102013\u2010093164"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2016.08.011"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546515618380"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23477"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/wics.1226"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1198\/1061860043010"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2009.09.013"},{"key":"e_1_2_8_44_1","unstructured":"W. Z.HortonFunctionalMixedEffects.Rpkg. Published online2022 https:\/\/github.com\/wzhorton\/FunctionalMixedEffects.Rpkg."},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1037\/a0015808"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrrheum.2010.212"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.20440"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00264\u2010024\u201006108\u20105"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.42744"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0838.2000.010004186.x"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1177\/1941738109350438"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000002969"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2023.105979"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.25142"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2014.03.011"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports\u20102021\u2010105311"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiomech.2020.105014"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2018.05.043"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.26101"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067\u2010024\u201006898\u20104"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2021.03.009"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1210\/jendso\/bvaa098"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.70196","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jor.70196","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.70196","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T02:32:31Z","timestamp":1779330751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.70196"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":61,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1002\/jor.70196"],"URL":"https:\/\/doi.org\/10.1002\/jor.70196","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-07-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70196"}}