{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T05:07:24Z","timestamp":1779772044073,"version":"3.53.1"},"reference-count":73,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T00:00:00Z","timestamp":1778371200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["IC180100024"],"award-info":[{"award-number":["IC180100024"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["FT230100524"],"award-info":[{"award-number":["FT230100524"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Changes in mechanical loading following total knee arthroplasty (TKA) are a critical factor that is important to understand with respect to component fixation. The aims of this study were to estimate medial, lateral, and total knee joint contact forces preoperatively, and then at 3\u2010, 6\u2010, and 12\u2010months postoperatively. Joint reaction forces (JRFs) were estimated using an electromyography (EMG) informed musculoskeletal modeling workflow with models scaled using computed tomography (CT) scans and weightbearing X\u2010rays, for lower limb alignment. Joint loading peak values and impulses were estimated in 22 participants awaiting primary TKA for osteoarthritis (OA) (median age, range: 69, 49\u201380 years; median BMI, range: 33, 25\u201340\u2009kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    ) during level gait and sit\u2010to\u2010stand at each timepoint. Medial, lateral, and total JRF peak values and impulses reduced significantly postoperatively at 3\u2010months and did not return to preoperative values at 12\u2010months for either activity. During level gait, mean total JRF peak values reduced by 0.72 BW (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) (medial mean difference: 0.39 BW,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001; lateral mean difference: 0.23 BW,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001) at 3\u2010months post\u2010surgery. A similar trend was observed in the sit\u2010to\u2010stand activity with a mean decrease of 0.44 BW in the peak total JRF at 3\u2010months (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). Impulse values followed a similar trend to the peak values. Clinical relevance: People do not return to preoperative JRFs even at 12\u2010months post\u2010TKA, and this may be a contributing factor for previously reported decreases in BMD around femoral and tibial components.\n                  <\/jats:p>","DOI":"10.1002\/jor.70222","type":"journal-article","created":{"date-parts":[[2026,5,10]],"date-time":"2026-05-10T10:17:36Z","timestamp":1778408256000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Joint Reaction Forces Decrease Following Total Knee Arthroplasty up to 12\u2010Months Post\u2010Surgery"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-5551-0188","authenticated-orcid":false,"given":"Salindi P.","family":"Herath","sequence":"first","affiliation":[{"name":"College of Science and Engineering, Medical Device Research Institute Flinders University Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hobbs","sequence":"additional","affiliation":[{"name":"College of Science and Engineering, Medical Device Research Institute Flinders University Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominic","family":"Thewlis","sequence":"additional","affiliation":[{"name":"Centre for Orthopaedic &amp; Trauma Research Adelaide University Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3421-3752","authenticated-orcid":false,"given":"Christopher","family":"Wilson","sequence":"additional","affiliation":[{"name":"College of Medicine and Public Health Flinders University Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Taylor","sequence":"additional","affiliation":[{"name":"College of Science and Engineering, Medical Device Research Institute Flinders University Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,10]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"CJRR Annual Report: Hip and Knee Replacements in Canada, Ottawa","author":"CJRR, C. 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