{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T06:02:13Z","timestamp":1779775333063,"version":"3.53.1"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study aimed to investigate the impact of COVID\u201019\u2013related activity restrictions on bone mineral density (BMD) and muscle mass in postmenopausal women undergoing treatment for osteoporosis. Patients who maintained regular clinic visits and continued pharmacological therapy were retrospectively analyzed. BMD and whole\u2010body muscle mass were assessed using dual\u2010energy X\u2010ray absorptiometry during the pre\u2010pandemic and pandemic periods, and changes were evaluated using the percentage of the young adult mean (%YAM). Exercise habits and dietary patterns were assessed using structured questionnaires. During the pandemic, approximately 40% of participants discontinued regular exercise. In contrast, dietary patterns and nutritional markers, including albumin and total protein, remained stable. Significant declines in %YAM were observed at the lumbar spine, femoral neck, and total hip, with greater reductions in the lumbar spine. Muscle mass also decreased significantly across all regions, with more pronounced reductions in the upper extremities. Changes in bone turnover markers suggested a shift toward a high\u2010turnover state. Despite continued treatment and clinical follow\u2010up, both bone and muscle parameters deteriorated during the pandemic. These findings indicate that reduced physical activity may adversely affect musculoskeletal health in patients with osteoporosis, even under appropriate pharmacological management. Strategies incorporating home\u2010based exercise interventions may be essential to mitigate such effects during periods of restricted mobility.<\/jats:p>","DOI":"10.1002\/jor.70225","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T10:24:15Z","timestamp":1778927055000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Importance of Exercise Habits for Preventing Osteoporosis in Postmenopausal Women: Insights From the COVID\u201019 Pandemic"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4122-7119","authenticated-orcid":false,"given":"Issei","family":"Shinohara","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Kusunose","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanako","family":"Nishimoto","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"},{"name":"Orthopaedic Surgery Kobe Rosai Hospital Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuyuki","family":"Inui","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9612-5785","authenticated-orcid":false,"given":"Yutaka","family":"Mifune","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Yamaura","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2915-9211","authenticated-orcid":false,"given":"Yutaka","family":"Ehara","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsaku","family":"Takigami","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Osawa","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daiji","family":"Nakabayashi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanobu","family":"Higashi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryota","family":"Wakamatsu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4587-0029","authenticated-orcid":false,"given":"Tomoyuki","family":"Matsumoto","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery Kobe University Graduate School of Medicine Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,16]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-021-00858-9"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lanwpc.2020.100016"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603-020-1501-6"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1590\/2359-3997000000011"},{"key":"e_1_2_14_6_1","doi-asserted-by":"crossref","unstructured":"1993. 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