{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:33:57Z","timestamp":1782974037565,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,24]],"date-time":"2026-05-24T00:00:00Z","timestamp":1779580800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["RX003608"],"award-info":[{"award-number":["RX003608"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["RX002970"],"award-info":[{"award-number":["RX002970"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007812","name":"University of Washington","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007812","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Distal femur fractures have a significant risk of healing complications, with potentially suboptimal fracture motion. We developed an in vivo method of quantifying fracture motion to support translational research. Five men and one woman (age 48.3\u2009\u00b1\u200924.9 years; weight 79.8\u2009\u00b1\u200912.9\u2009kg, mean\u2009\u00b1\u2009SD) underwent non\u2010weightbearing and weightbearing CT following plate (4) or nail (2) fixation of distal femur fractures (AO\/OTA 33) while recording static ground reaction forces. Subject\u2010specific models were generated, coordinate systems were established, and fragment poses were reconstructed to assess motion. Fracture motion was measurable and greater at the medial than the lateral aspects of fractures, with notable axial plane motion. Three\u2010dimensional (3D) displacement (mean\u2009\u00b1\u2009standard deviation [SD]) was greater at the medial than lateral fracture (4.4\u2009\u00b1\u20092.6 vs. 3.5\u2009\u00b1\u20092.6\u2009mm,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.047), including mean proximal\u2010distal displacement at the medial fracture (2.0\u2009\u00b1\u20093.0\u2009mm) versus lateral fracture (0.8\u2009\u00b1\u20093.2\u2009mm,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.030), and mean axial plane displacement at the medial (3.5\u2009\u00b1\u20091.6\u2009mm) versus lateral (2.6\u2009\u00b1\u20091.6\u2009mm,\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.009) fracture. Axial plane displacement was similar to proximal\u2010distal displacement at the medial (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.318) and lateral (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.488) fracture. 3D and axial plane displacement were moderately associated with load, while proximal\u2010distal displacement was minimally associated with load. Weightbearing magnitude only modestly explained intersubject differences in motion. This method allows exploration of relationships between fracture motion, fracture pattern, fixation, loading, and healing.\n                  <\/jats:p>","DOI":"10.1002\/jor.70229","type":"journal-article","created":{"date-parts":[[2026,5,25]],"date-time":"2026-05-25T04:56:08Z","timestamp":1779684968000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["In Vivo Assessment of Distal Femur Fracture Motion via Weightbearing CT"],"prefix":"10.1002","volume":"44","author":[{"given":"William D.","family":"Lack","sequence":"first","affiliation":[{"name":"RR&amp;D Center for Limb Loss and MoBility (CLiMB) VA Puget Sound Health Care System Seattle Washington USA"},{"name":"Department of Orthopaedic Surgery and Sports Medicine University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4982-7714","authenticated-orcid":false,"given":"William R.","family":"Ledoux","sequence":"additional","affiliation":[{"name":"RR&amp;D Center for Limb Loss and MoBility (CLiMB) VA Puget Sound Health Care System Seattle Washington USA"},{"name":"Department of Orthopaedic Surgery and Sports Medicine University of Washington Seattle Washington USA"},{"name":"Department of Mechanical Engineering University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Entress","sequence":"additional","affiliation":[{"name":"RR&amp;D Center for Limb Loss and MoBility (CLiMB) VA Puget Sound Health Care System Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Crutcher","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0104-4027","authenticated-orcid":false,"given":"Scott","family":"Telfer","sequence":"additional","affiliation":[{"name":"RR&amp;D Center for Limb Loss and MoBility (CLiMB) VA Puget Sound Health Care System Seattle Washington USA"},{"name":"Department of Orthopaedic Surgery and Sports Medicine University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Thorhauer","sequence":"additional","affiliation":[{"name":"RR&amp;D Center for Limb Loss and MoBility (CLiMB) VA Puget Sound Health Care System Seattle Washington USA"},{"name":"Department of Orthopaedic Surgery and Sports Medicine University of Washington Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199810001-00015"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-200203000-00025"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.67B4.4030869"},{"key":"e_1_2_10_5_1","first-page":"73","article-title":"Does Locked Plating of Periprosthetic Supracondylar Femur Fractures Promote Bone Healing by Callus Formation? 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