{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T06:34:15Z","timestamp":1782974055375,"version":"3.54.5"},"reference-count":41,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T00:00:00Z","timestamp":1780963200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000090","name":"Congressionally Directed Medical Research Programs","doi-asserted-by":"publisher","award":["W81XWH\u201020\u20101\u20100040"],"award-info":[{"award-number":["W81XWH\u201020\u20101\u20100040"]}],"id":[{"id":"10.13039\/100000090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008542","name":"Arthroscopy Association of North America","doi-asserted-by":"publisher","award":["2204"],"award-info":[{"award-number":["2204"]}],"id":[{"id":"10.13039\/100008542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    The characteristics of patients that promote progressive cartilage degradation following patellar dislocations are not well understood. The study hypothesis is that associations relating cartilage degradation to low BMI, high activity and youth in the early months following patellar dislocation are not exhibited for contralateral knees or a longer time from injury. Quantitative MRI\u2010based evaluation of injured and contralateral knees occurred within 5 months of a unilateral patellar dislocation (baseline evaluation, 36 subjects) and beyond 5 months (follow\u2010up evaluation, 20 subjects). Linear regressions correlated T1\u03c1 relaxation times for regions of patellofemoral and tibiofemoral cartilage against body mass index, age, and activity level. Long relaxation times indicate cartilage degradation. Baseline T1\u03c1 relaxation times were significantly inversely correlated with body mass index throughout patellofemoral cartilage for injured knees (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001 to 0.03). Similar relationships were identified for all regions of patellar cartilage for contralateral knees (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.011 to 0.015). Injured and contralateral T1\u03c1 relaxation times were also correlated with activity level (positive correlation) and age (inverse correlation) for various regions of cartilage (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001 to 0.047). The only significant correlations for the follow\u2010up groups related increasing body mass index to long cartilage T1\u03c1 relaxation times for the contralateral medial trochlear groove, femoral condyles, and lateral tibial plateau (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009=\u20090.008 to 0.026). The attributes of a dislocation that determine characteristics influencing cartilage are common to both knees but dissipate over time. A systemic, transient inflammatory response to injury could explain the short\u2010term similarities between injured and contralateral knees following dislocation.\n                  <\/jats:p>","DOI":"10.1002\/jor.70233","type":"journal-article","created":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T09:45:58Z","timestamp":1780998358000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Associations\n                    <b>B<\/b>\n                    etween Patient Characteristics and Cartilage T1\u03c1 Relaxation Times Vary Over Time Following Patellar Dislocation"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9298-2915","authenticated-orcid":false,"given":"John J.","family":"Elias","sequence":"first","affiliation":[{"name":"Cleveland Clinic Akron General Akron Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lutul D.","family":"Farrow","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Lartey","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet Hakan","family":"Ok","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Li","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8902-6316","authenticated-orcid":false,"given":"Mingrui","family":"Yang","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl S.","family":"Winalski","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaojuan","family":"Li","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/1941738117725055"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-8063(03)00401-8"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516687549"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-012-2493-3"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/19476035221102570"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465231205562"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.28857"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516680604"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","DOI":"10.1177\/2325967119867085","article-title":"Predictors of Radiographic Osteoarthritis 2 to 3 Years After Anterior Cruciate Ligament Reconstruction: Data From the MOON On\u2010Site Nested Cohort","volume":"7","author":"Group M. K.","year":"2019","journal-title":"Orthopaedic Journal of Sports Medicine"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465231162105"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00167-019-05461-y"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2022.110991"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-018-1727-4"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/2325967120943874"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.02.006"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/17453674.2021.1882131"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2006.07.007"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/23259671251334634"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465221074662"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.973870"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2024.09.001"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513496548"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.knee.2021.07.004"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546520980431"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.26102"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.28111"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2020.07.005"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2015.07.006"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.29369"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000003386"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2013.06.022"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.30419"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.18.20026"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00330-025-11806-8"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546517749834"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.11327"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar3216"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465251401555"},{"key":"e_1_2_9_41_1","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1001\/jama.2023.19205","article-title":"Study: Waist\u2010to\u2010Hip Ratio Might Predict Mortality Better Than BMI","volume":"330","author":"Harris E.","year":"2023","journal-title":"Journal of the American Medical Association"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/72.3.694"}],"container-title":["Journal of Orthopaedic Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.70233","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jor.70233","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jor.70233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T05:09:28Z","timestamp":1782968968000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/jor.70233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":41,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1002\/jor.70233"],"URL":"https:\/\/doi.org\/10.1002\/jor.70233","archive":["Portico"],"relation":{},"ISSN":["0736-0266","1554-527X"],"issn-type":[{"value":"0736-0266","type":"print"},{"value":"1554-527X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"2025-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70233"}}