{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T04:36:19Z","timestamp":1774326979809,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T00:00:00Z","timestamp":1569369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["Joint\u2010PhD Training Program"],"award-info":[{"award-number":["Joint\u2010PhD Training Program"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004543","name":"China Scholarship Council","doi-asserted-by":"publisher","award":["201806210415"],"award-info":[{"award-number":["201806210415"]}],"id":[{"id":"10.13039\/501100004543","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Studies on malnutrition suggest low body mass index (BMI) may be associated with poor clinical outcomes. We investigated published data to identify whether low BMI could predict short\u2010term and long\u2010term clinical outcomes in Asian hospitalized patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A search was conducted in the PubMed database including terms \u201cbody mass index\u201d or \u201cBMI\u201d or \u201cmalnutrition\u201d or \u201cundernutrition\u201d AND \u201cAsia\u201d or \u201cAsian\u201d AND \u201coutcome\u201d or \u201ccomplication\u201d or \u201cmortality\u201d or \u201csurvival\u201d or \u201cICU\u201d for publications in English in the past 10\u00a0years. Papers with data and clinical outcomes from Asian hospitalized patients with BMI &lt;18.5\u00a0kg\/m<jats:sup>2<\/jats:sup> and sample size &gt;50 were included. Forest plots were constructed to determine the odds of hospital complications, hospital mortality, intensive care unit (ICU) mortality, and 5\u2010year mortality in patients with BMI &lt;18.5\u00a0kg\/m<jats:sup>2<\/jats:sup> vs BMI \u226518.5\u00a0kg\/m<jats:sup>2<\/jats:sup>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twenty\u2010three studies were included, 16 of which were analyzed for the association between low BMI and clinical outcomes. The prevalence of BMI &lt;18.5\u00a0kg\/m<jats:sup>2<\/jats:sup> varied from 3% to 48% in different disease settings and Asian areas. Patients with BMI &lt;18.5\u00a0kg\/m<jats:sup>2<\/jats:sup> had significantly higher ICU mortality (odds ratio [OR], 1.92; 95% CI, 1.84\u20132.01), higher hospital mortality (OR, 2.48; 95% CI, 2.42\u20132.55), and higher 5\u2010year mortality (OR, 2.74; 95% CI, 2.08\u20133.63). Complications during hospital stay were significantly higher in patients with BMI &lt;18.5\u00a0kg\/m<jats:sup>2<\/jats:sup> (OR, 1.99; 95% CI, 1.65\u20132.40).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Low BMI defined as &lt;18.5\u00a0kg\/m<jats:sup>2<\/jats:sup> may predict worse short\u2010term and longer\u2010term outcomes in Asian hospitalized patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.1708","type":"journal-article","created":{"date-parts":[[2019,9,25]],"date-time":"2019-09-25T21:39:05Z","timestamp":1569447545000},"page":"722-728","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Does Low Body Mass Index Predict Mortality in Asian Hospitalized Patients?"],"prefix":"10.1002","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5492-0553","authenticated-orcid":false,"given":"Zhigang","family":"Xue","sequence":"first","affiliation":[{"name":"Peking Union 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