{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T21:36:24Z","timestamp":1791840984427,"version":"4.3.4"},"reference-count":92,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012690","name":"Nestl\u00e9 Nutrition Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012690","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011947","name":"Abbott Nutrition","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011947","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007535","name":"B. 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The purpose of this project was to conduct an evidence review and evaluate claims analyses to understand the financial and quality impact of nutrition support therapy on high\u2010priority therapeutic conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Task 1 included a review of existing literature from 2013 to 2018 to identify evidence that demonstrated the clinical and economic impact of nutrition intervention on patient outcomes across 13 therapeutic areas (TAs). In Task 2, analytic claims modeling was performed using the Medicare Parts A and B claims 5% sample dataset. Beneficiaries diagnosed in 5 selected TAs (sepsis, gastrointestinal [GI] cancer, hospital\u2010acquired infections, surgical complications, and pancreatitis) were identified in the studies from Task 1, and their care costs were modeled based on nutrition intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Beginning with 1099 identified articles, 43 articles met the criteria, with a final 8 articles used for the Medicare claims modeling. As examples of the modeling demonstrated, the use of advanced enteral nutrition formula could save at least $52 million annually in a sepsis population. The total projected annual cost savings from the 5 TAs was $580 million.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Overall, optimization of nutrition support therapy for specific patient populations is estimated to reduce Medicare spending by millions of dollars per year across key TAs. These findings demonstrate the evidence\u2010based value proposition of timely nutrition support to improve clinical outcomes and yield substantial cost savings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpen.1768","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T06:45:52Z","timestamp":1580280352000},"page":"395-406","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Value of Nutrition Support Therapy: Impact on Clinical and Economic Outcomes in the United States"],"prefix":"10.1002","volume":"44","author":[{"given":"Renay","family":"Tyler","sequence":"first","affiliation":[{"name":"University of Maryland Medical Center  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8506-7244","authenticated-orcid":false,"given":"Albert","family":"Barrocas","sequence":"additional","affiliation":[{"name":"Tulane School of Medicine  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2850-246X","authenticated-orcid":false,"given":"Peggi","family":"Guenter","sequence":"additional","affiliation":[{"name":"Clinical Practice, Quality, and Advocacy American Society for Parenteral Nutrition  Silver Spring Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krysmaru","family":"Araujo Torres","sequence":"additional","affiliation":[{"name":"Nestl\u00e9 Health Science  Bridgewater New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew L.","family":"Bechtold","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology &amp; Hepatology Department of Medicine University Hospital &amp; Clinics  Columbia Missouri USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingtak\u2010Neander","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Pharmacy Interdisciplinary Faculty Nutritional Sciences Program University of Washington  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"Collier","sequence":"additional","affiliation":[{"name":"Virginia Tech Carilion School of Medicine  Roanoke Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nilsa A.","family":"Collins","sequence":"additional","affiliation":[{"name":"Clinical Integration Programs WellStar Clinical Partners Marietta  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Evans","sequence":"additional","affiliation":[{"name":"Ohio Health Trauma and Surgical Services  Columbus Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karim","family":"Godamunne","sequence":"additional","affiliation":[{"name":"North Fulton Hospitalists Group  Roswell Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cindy","family":"Hamilton","sequence":"additional","affiliation":[{"name":"Digestive Disease and Surgery Institute Cleveland Clinic  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beverly J. 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