{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T04:56:01Z","timestamp":1764305761470,"version":"build-2065373602"},"reference-count":8,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T00:00:00Z","timestamp":1584489600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Teduglutide (TED) reduces the need for parenteral support (PS) in patients with short\u2010bowel syndrome with intestinal failure (SBS\u2010IF). It is a glucagon\u2010like peptide\u20102 analog that improves absorption, induces the expansion of the absorptive epithelium in the small intestine, and may be used in patients with SBS\u2010IF after a 6\u2010 to 12\u2010month adaptation period, if PS is always necessary. We described the functional and morphological effect of TED in a 40\u2010year\u2010old female patient with SBS\u2010IF due to Crohn's disease who underwent terminal jejunostomy after 12 months of drug exposition. Marked hypertrophy of the villi was detected by endoscopic capsule and confirmed by histological measurements. This is the first publication demonstrating an increase in intestinal absorption in an SBS\u2010IF patient treated with TED because of a morphological adaptation of the small bowel, with hyperplasia confirmed by capsule endoscopy and histology. The capsule endoscopy, a noninvasive exploration of the gut, could be evaluated to monitor the real efficacy of treatments with growth factors in SBS patients.<\/jats:p>","DOI":"10.1002\/jpen.1805","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T16:50:16Z","timestamp":1584550216000},"page":"940-943","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Small\u2010Bowel Adaptation: A Case of Morphological Changes Induced by Teduglutide in Short\u2010Bowel Syndrome With Intestinal Failure"],"prefix":"10.1002","volume":"44","author":[{"given":"Thomas","family":"Mouillot","sequence":"first","affiliation":[{"name":"Gastroenterology, IBD and Nutritional Support Department H\u00f4pital Beaujon Assistance Publique\u2010H\u00f4pitaux de Paris  Clichy France"},{"name":"Hepatology and Gastroenterology Department F. 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