{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T23:35:49Z","timestamp":1792798549895,"version":"4.5.0"},"reference-count":28,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,7,17]],"date-time":"2020-07-17T00:00:00Z","timestamp":1594944000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Aim was to investigate the association between quality of life (QoL), bowel anatomy, and the need for home parenteral support (HPS) volume in patients with nonmalignant short\u2010bowel syndrome (SBS) and intestinal failure (IF).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The SBS\u2010QoL scale was used in a cross\u2010sectional study of 95 nonmalignant SBS\u2010IF patients. Sum QoL scores (0: best, 170: worst) were calculated. Patients were defined as having a small bowel (\u2264200 cm), and patients with jejunostomy or ileostomy were subclassified based on functional small\u2010bowel length (cm) into 4 anatomy subgroups: 1a\u20131d (0\u201349, 50\u201399, 100\u2013149, 150\u2013200 cm, respectively). Multiple linear regression analyses explored associations between QoL, patient groups, and HPS volume, adjusting for age, sex, body mass index, and education.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Complete data were obtained from 60 patients. HPS volume was associated with a worse SBS\u2010QoL score (L\/d, \u03b2 = 7.91; SE = 3.90; <jats:italic>P<\/jats:italic> = .048), but male sex associated with improvement (\u03b2 = \u221226.28; SE = 11.06; <jats:italic>P<\/jats:italic> = .021). No differences in sum QoL were seen between the benign SBS\u2010IF subgroups 1a\u2013d (<jats:italic>P<\/jats:italic> = .210). Multivariate regression analyses showed that patients with a small\u2010bowel stoma, a small\u2010bowel length &lt;50 cm was associated with a significantly worse\/higher SBS\u2010QoL score compared with a length &gt;50 cm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients with benign SBS\u2010IF, high HPS volume was associated with poor QoL. Also, jejunostomy or ileostomy with small\u2010bowel length &lt;50 cm was associated with impaired QoL. These findings support rehabilitation strategies that reduce fecal losses and decrease HPS needs.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.1958","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T04:46:13Z","timestamp":1593665173000},"page":"926-932","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["High Parenteral Support Volume Is Associated With Reduced Quality of Life Determined by the Short\u2010Bowel Syndrome Quality of Life Scale in Nonmalignant Intestinal Failure Patients"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4034-7194","authenticated-orcid":false,"given":"Cecilie Bagi","family":"Nordsten","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9214-046X","authenticated-orcid":false,"given":"Stig","family":"Molsted","sequence":"additional","affiliation":[{"name":"Department of Clinical Research Nordsjaellands Hospital  Hilleroed Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Bangsgaard","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian A.","family":"Fuglsang","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher F.","family":"Brandt","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6195-9894","authenticated-orcid":false,"given":"Mads J.","family":"Niemann","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology The Copenhagen Muscle Research Centre Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palle B.","family":"Jeppesen","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Rigshospitalet  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,7,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2016.01.020"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607109348612"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90065-6"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0261-5614(03)00042-6"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.6.844"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2006.01.001"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2006.05.035"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607113517717"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00152192-200103000-00007"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607113512678"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2004.12.009"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2009.02.008"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(03)00074-4"},{"key":"e_1_2_9_15_1","first-page":"201","article-title":"Home parenteral nutrition in adults: the current use of an experienced method","volume":"62","author":"Van Gossum A","year":"1999","journal-title":"Acta Gastroenterol Belg"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607105029003162"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1079\/BJN20051533"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2012.12.001"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2013.03.016"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jpen.1588"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607116655449"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2753.2000.00238.x"},{"key":"e_1_2_9_23_1","unstructured":"U.S. Food and Administration.https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/203441s012lbl.pdf. 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