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The clinical presentation of COVID\u201019 ranges from that of being asymptomatic to developing a fatal illness characterized by multiple organ involvement. Approximately 20% of the patients will require hospitalization; one\u2010quarter of hospitalized patients will develop severe COVID\u201019 requiring admission to the intensive care unit, most frequently, with acute respiratory failure. An ongoing effort is being made to identify the patients that will develop severe COVID\u201019. Overall, patients present with 3 different phenotypes of nutrition risk: (1) the frail older patient, (2) the patient with severe ongoing chronic illness, and (3) the patient with severe and morbid obesity. These 3 phenotypes represent different nutrition risks and diverse nutrition interventions. This article explores the different potential approaches to nutrition intervention in patients with COVID\u201019, evaluating, in this process, the challenges faced in the implementation of guidelines written by different societies.<\/jats:p>","DOI":"10.1002\/jpen.2005","type":"journal-article","created":{"date-parts":[[2020,8,24]],"date-time":"2020-08-24T19:36:49Z","timestamp":1598297809000},"page":"1369-1375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Lessons Learned in Nutrition Therapy in Patients With Severe COVID\u201019"],"prefix":"10.1002","volume":"44","author":[{"given":"Juan B.","family":"Ochoa","sequence":"first","affiliation":[{"name":"Department of Surgery Ochsner Medical Center\u2013New Orleans  New Orleans Louisiana USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0709-0307","authenticated-orcid":false,"given":"Diana","family":"C\u00e1rdenas","sequence":"additional","affiliation":[{"name":"Department of Medicine Universidad El Bosque  Bogota Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda E.","family":"Goiburu","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias Medicas Universidad Nacional de Asuncion  Asuncion Paraguay"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Berm\u00fadez","sequence":"additional","affiliation":[{"name":"Nutricion Clinica Clinica del Country  Bogota Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando","family":"Carrasco","sequence":"additional","affiliation":[{"name":"Faculty of Medicine University of Chile  Santiago de Chile Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3503-4302","authenticated-orcid":false,"given":"M. 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