{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:11:56Z","timestamp":1760883116814,"version":"build-2065373602"},"reference-count":24,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,10,19]],"date-time":"2020-10-19T00:00:00Z","timestamp":1603065600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of the study was to assess the effects of computerized provider order entry (CPOE) for parenteral nutrition (PN) on selected clinical parameters of extremely low\u2010birth\u2010weight (ELBW) neonates in a tertiary neonatal intensive care unit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study was a retrospective data analysis of preterm infants born over a 1\u2010year period before and after introduction of CPOE. PN composition during the first 2 weeks of life, change in weight, head circumference and body length <jats:italic>z<\/jats:italic>\u2010scores were assessed. Duration of PN and selected neonatal complications were compared. Logistic regression was used to adjust for confounding variables (sex, birth weight, and birth\u2010gestational age).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Ninety\u2010four patients in 2 equal groups were analyzed. Birth weight (median 810 vs 825 g) and gestational age (27 vs 27 weeks) were comparable. After adjustment for confounding variables, on the first and seventh day of life, significantly more energy (<jats:italic>P<\/jats:italic> &lt; .001), protein (<jats:italic>P<\/jats:italic> &lt; .001), lipid (<jats:italic>P<\/jats:italic> &lt; .03), and carbohydrate (<jats:italic>P<\/jats:italic> &lt; .02) were administered in the CPOE group than in the manually calculated (MC) prescriptions group. The CPOE group had lower weight loss (<jats:italic>P<\/jats:italic> &lt; .001), a significant improvement in linear growth, and faster regain of birth weight (<jats:italic>P<\/jats:italic> &lt; .01) compared with the MC group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The CPOE positively influences the quality of PN in ELBW infants. It also significantly reduced initial weight loss, time to regain birth weight, and linear growth. It may also have beneficial effects on selected clinical outcomes, which requires further study.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.2022","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T10:44:00Z","timestamp":1601981040000},"page":"1197-1203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of Computer Calculation Program on Quality of Individualized Parenteral Nutrition and Selected Clinical Parameters of Extremely Low\u2010Birth\u2010Weight Infants"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4164-8941","authenticated-orcid":false,"given":"Marika","family":"Oczujda","sequence":"first","affiliation":[{"name":"Department of Neonatology, Neonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit Poznan University of Medical Sciences  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Izabela","family":"Miechowicz","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Statistics Poznan University of Medical Sciences  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Szymankiewicz\u2010Br\u0119borowicz","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Neonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit Poznan University of Medical Sciences  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Czech\u2010Szczapa","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine Epidemiology Unit Poznan University of Medical Sciences  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark J.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Neonatal Medicine University Hospital Southampton National Health Service Foundation Trust  Southampton UK"},{"name":"National Institute for Health Research Southampton Biomedical Research Centre University Hospital Southampton National Health Service Foundation Trust and University of Southampton  Southampton UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomasz","family":"Szczapa","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Neonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit Poznan University of Medical Sciences  Poznan Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.06.951"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-016-0648-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e318217f4f1"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-0211"},{"key":"e_1_2_8_6_1","first-page":"93","volume-title":"Standards of medical care for neonates in Poland. 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