{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:29:26Z","timestamp":1791401366565,"version":"4.3.3"},"reference-count":9,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T00:00:00Z","timestamp":1605052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Critically ill patients frequently develop feeding intolerance, which is difficult to predict. In healthy subjects, gastric motility, assessed by nasogastric balloon tube, correlated with gastric emptying. We now investigated this correlation in critically ill patients, as well as the feasibility and safety of such application in a pilot study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Endotracheally intubated adults scheduled to receive enteral nutrition (EN) were included. After insertion of a double\u2010lumen nasogastric balloon tube and radiographic confirmation of position, balloon pressure was recorded for 10 hours after inflation (4 hours fasted, 2 hours during administration of <jats:sup>13<\/jats:sup>C\u2010labeled EN, and 4 hours postprandially). Gastric motility was expressed as Gastric Balloon Motility Index (GBMI), reflecting the fraction of time in which phasic gastric contractions occurred. Gastric emptying was assessed by <jats:sup>13<\/jats:sup>C\u2010octanoate breath test and expressed as gastric half\u2010emptying time (GET\u00bd). Correlation between GBMI (assessed in different time intervals) and GET\u00bd was investigated by Pearson\/Spearman correlation. Feasibility was defined as the success of tube placement and pressure recording. Safety was assessed based on adverse device effects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Thirty patients were enrolled, of whom 19 had paired GBMI and GET\u00bd data. There was no correlation between GBMI and GET\u00bd. The tube was successfully placed in 28\/30 (93.3%) patients. In 3\/28 (10.7%) patients, balloon leakage precluded analysis. Two safety events were directly linked to the device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This pilot study showed no significant correlation between balloon\u2010assessed gastric motility and emptying in critically ill patients. The feasibility\/safety profile of the balloon tube appears similar to that of standard nasogastric tubes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.2037","type":"journal-article","created":{"date-parts":[[2020,10,23]],"date-time":"2020-10-23T11:39:38Z","timestamp":1603453178000},"page":"1779-1784","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Continuous Assessment of Gastric Motility and Its Relation to Gastric Emptying in Adult Critically Ill Patients"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7812-1740","authenticated-orcid":false,"given":"Nick","family":"Goelen","sequence":"first","affiliation":[{"name":"Translational Research Center for Gastrointestinal Disorders KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pieter","family":"Janssen","sequence":"additional","affiliation":[{"name":"Translational Research Center for Gastrointestinal Disorders KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Tack","sequence":"additional","affiliation":[{"name":"Translational Research Center for Gastrointestinal Disorders KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Morales","sequence":"additional","affiliation":[{"name":"Center for Dynamical Systems, Signal Processing and Data Analytics KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tine","family":"Honinx","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greet","family":"Van den Berghe","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Casaer","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2470-6393","authenticated-orcid":false,"given":"Jan","family":"Gunst","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine, Laboratory of Intensive Care Medicine KU Leuven  Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,11,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1304623"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-02889-4"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.08.037"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607115621863"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2018.07.009"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.196377"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13733"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/011542650602100140"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc12791"}],"container-title":["Journal of Parenteral and Enteral 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