{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T16:11:46Z","timestamp":1760890306626,"version":"build-2065373602"},"reference-count":9,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T00:00:00Z","timestamp":1620259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2021,8]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>The direct effect of the coronavirus disease 2019 (COVID\u201019) pandemic on patients with intestinal failure (IF) has not been described.<\/jats:p><\/jats:sec>Methods<\/jats:title>We conducted a nationwide study of UK IF centers to evaluate the infection rates, presentations, and outcomes in patients with types 2 and 3 IF.<\/jats:p><\/jats:sec>Results<\/jats:title>A total of 45 patients with IF contracted COVID\u201019 between March and August 2020; this included 26 of 2191 (1.2%) home parenteral nutrition (HPN)\u2013dependent adults and 19 of 298 (6.4%) adults hospitalized with type 2 IF. The proportion of patients receiving nursing care for HPN administration was higher in those with community\u2010acquired COVID\u201019 (66.7%) than the proportion in the entire HPN cohort (26.1%; P<\/jats:italic> < .01). Two HPN\u2010dependent and 1 hospitalized patient with type 2 IF died as a direct consequence of the virus (6.7% of 45 patients with types 2 or 3 infected).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This is the first study to describe the outcomes of COVID\u201019 in a large cohort of patients requiring long\u2010term PN. Methods to reduce hospital and community nosocomial spread would likely be beneficial.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.2087","type":"journal-article","created":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T23:55:25Z","timestamp":1613519725000},"page":"1369-1375","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["COVID\u201019 infection in patients with intestinal failure: UK experience"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2682-772X","authenticated-orcid":false,"given":"P. 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