{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:31:04Z","timestamp":1792438264859,"version":"4.5.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["Financial Code 001"],"award-info":[{"award-number":["Financial Code 001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Early identification of patients in the pediatric intensive care unit (PICU) at risk of nutritional status (NS) deterioration and poor outcomes is desirable.<\/jats:p><\/jats:sec><jats:sec><jats:label\/><jats:p>We aimed to identify factors associated with NS deterioration and prolonged PICU stay.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Prospective cohort study in eight Brazilian PICUs with children &lt;18 years with a PICU stay &gt;72h. We used multivariable logistic regression to identify the clinical, laboratory, and nutrition variables at admission that were associated with outcomes. NS deterioration was defined as the reduction in weight\u2010for\u2010age, body mass index\u2013for\u2010age or mid\u2010upper arm circumference\u2013for\u2010age <jats:italic>z<\/jats:italic>\u2010score \u22651 during PICU stay. Prolonged PICU stay was defined as \u226513 days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We enrolled 363 eligible patients, median age 11.3 months (interquartile range:3.1\u201345.6) and 46% had at least one complex chronic condition (CCC). NS deterioration was observed in 23% of participants and was associated with CCC (odds ratio [OR]:2.71; 95% confidence interval [CI]:1.44\u20135.09), after adjusting for severity risk score, leukocyte count, obesity, and PICU site. Prolonged PICU stay was associated with age &lt;2 years (OR:1.95; 95%CI:1.03\u20133.66), fluid overload (&gt;10%) over the first 72h (OR:2.66; 95%CI:1.50\u20134.73), and hypoalbuminemia (&lt;3.0 g\/dL) (OR:2.05; 95%CI:1.12\u20133.76), after adjusting for CCC, severity risk score, undernutrition, early nutrition therapy, and PICU site.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>CCC at admission was associated with NS deterioration. Age &lt;2 years, fluid overload, and hypoalbuminemia at PICU admission were associated with prolonged PICU stay. These factors must be further evaluated as part of an admission nutrition screening tool for critically ill children.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.2116","type":"journal-article","created":{"date-parts":[[2021,4,5]],"date-time":"2021-04-05T06:48:26Z","timestamp":1617605306000},"page":"330-338","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Admission factors associated with nutritional status deterioration and prolonged pediatric intensive care unit stay in critically ill children: PICU\u2010ScREEN multicenter study"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0492-0352","authenticated-orcid":false,"given":"Julia Carvalho","family":"Ventura","sequence":"first","affiliation":[{"name":"Department of Nutrition Federal University of Santa Catarina  Florian\u00f3polis 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