{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:17:27Z","timestamp":1760887047204,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Not all patients suffer from a severe course of severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) infection, demanding a definition of groups at risk. Short bowel syndrome (SBS) has been assumed to be a risk factor, because of the complexity of disease, the need for interdisciplinary care, and frequent contact with caretakers. We aimed to establish data on the course of infection and prevalence of SARS\u2010CoV\u20102 seropositivity in SBS patients in Germany.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January 2021 until January 2022 a total of 119 patients from three different tertiary care centers with SBS were included. All patients received an antibody test against the nucleocapsid (N) antigen and were asked to fill out a questionnaire, which included frequency of contact with medical personnel, risk behavior and worries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Sixty\u2010seven percent of SBS patients received parenteral nutrition with a median of 6 days per week. The seroprevalence of SARS\u2010CoV\u20102 antibodies was 7.6% (<jats:italic>n<\/jats:italic>\u2009=\u20099). Seven patients with positive antibodies had coronavirus disease 2019 (COVID\u201019) with a mild course. None of the patients were hospitalized or needed further treatment. There was no difference in willingness to take risks in SARS\u2010CoV\u20102 antibody\u2013positive and \u2013negative patients (<jats:italic>P<\/jats:italic>\u2009=\u20090.61). Patients were predominantly worried about the economy (61%) and transmitting COVID\u201019 (52%), less frequent (26%) about receiving insufficient medical treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>These are the first clinical results concerning SARS\u2010CoV\u20102 seropositivity and COVID\u201019 disease in patients with SBS. The seropositivity is comparable to national data, which we attribute to increased risk awareness and avoidance. Further studies are warranted to investigate effects of COVID\u201019 infection in SBS patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jpen.2410","type":"journal-article","created":{"date-parts":[[2022,5,26]],"date-time":"2022-05-26T07:53:30Z","timestamp":1653551610000},"page":"1404-1411","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe acute respiratory syndrome coronavirus 2 antibody prevalence in adult patients with short bowel syndrome\u2014A German multicenter cross\u2010sectional study"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7008-8795","authenticated-orcid":false,"given":"Elisabeth","family":"Bl\u00fcthner","sequence":"first","affiliation":[{"name":"Department of Hepatology and Gastroenterology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Campus Charit\u00e9 Mitte and Campus Virchow\u2010Klinikum Berlin Germany"},{"name":"BIH Charit\u00e9 Clinician Scientist Program Berlin Institute of Health (BIH) Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrich\u2010Frank","family":"Pape","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Gastroenterology Asklepios Clinic St. Georg Hamburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Blumenstein","sequence":"additional","affiliation":[{"name":"Medical Clinic 1 University Hospital Frankfurt Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanette","family":"Wichmann","sequence":"additional","affiliation":[{"name":"Medical Clinic 1 University Hospital Frankfurt Frankfurt am Main Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Tacke","sequence":"additional","affiliation":[{"name":"Department of Hepatology and Gastroenterology, Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Campus Charit\u00e9 Mitte and Campus Virchow\u2010Klinikum Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1879-4788","authenticated-orcid":false,"given":"Simon","family":"Moosburner","sequence":"additional","affiliation":[{"name":"BIH Charit\u00e9 Clinician Scientist Program Berlin Institute of Health (BIH) Berlin Germany"},{"name":"Department of Surgery Campus Charit\u00e9 Mitte, Campus Virchow\u2010Klinikum Charit\u00e9\u2014Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.37257"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2019716118"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28232-9"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2034545"},{"key":"e_1_2_11_6_1","unstructured":"European Centre for Disease Prevention and Control. 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