{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:27:58Z","timestamp":1791883678961,"version":"4.3.4"},"reference-count":51,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,4,11]],"date-time":"2024-04-11T00:00:00Z","timestamp":1712793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\n                      Children with chronic IF require long\u2010term home parenteral nutrition (HPN), administered through a central venous catheter. Catheter\u2010related bloodstream infection (CRBSI) with\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      is known to be a serious infection with a high mortality rate and risk of complications. A standardized protocol on the management of\n                      <jats:italic>S aureus<\/jats:italic>\n                      CRBSIs in children receiving HPN is lacking. The aim of this study is to evaluate the effectiveness and safety of the current management in an HPN expertise center in the Netherlands.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective descriptive cohort study between 2013 and 2022 on children 0\u201318 years of age with chronic IF requiring long\u2010term HPN. Our primary outcomes were the incidence of\n                      <jats:italic>S aureus<\/jats:italic>\n                      CRBSI per 1000 catheter days, catheter salvage attempt rate, and successful catheter salvage rate. Our secondary outcomes included complications and mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 74 patients (39 male; 53%) were included, covering 327.8 catheter years. Twenty\u2010eight patients (38%) had a total of 52\n                      <jats:italic>S aureus<\/jats:italic>\n                      CRBSIs, with an incidence rate of 0.4 per 1000 catheter days. The catheter salvage attempt rate was 44% (23\/52). The successful catheter salvage rate was 100%. No relapse occurred, and no removal was needed after catheter salvage. All complications that occurred were already present at admission before the decision to remove the catheter or not. No patients died because of an\n                      <jats:italic>S aureus<\/jats:italic>\n                      CRBSI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Catheter salvage in\n                      <jats:italic>S aureus<\/jats:italic>\n                      CRBSIs in children receiving HPN can be attempted after careful consideration by a multidisciplinary team in an HPN expertise center.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpen.2630","type":"journal-article","created":{"date-parts":[[2024,4,12]],"date-time":"2024-04-12T01:59:36Z","timestamp":1712887176000},"page":"486-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Catheter salvage or removal in catheter\u2010related bloodstream infections with\n                    <i>Staphylococcus aureus<\/i>\n                    in children with chronic intestinal failure receiving home parenteral nutrition and the use of prophylactic taurolidine catheter lock solution: A descriptive cohort study"],"prefix":"10.1002","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2425-979X","authenticated-orcid":false,"given":"Aysenur","family":"Demirok","sequence":"first","affiliation":[{"name":"Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital Amsterdam University Medical Centers University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David H. 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Nutrition, Emma Children's Hospital Amsterdam University Medical Centers University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merit M.","family":"Tabbers","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology, Hepatology and Nutrition, Emma Children's Hospital Amsterdam University Medical Centers University of Amsterdam Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,11]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2016.02.011"},{"key":"e_1_2_9_3_1","first-page":"7771","article-title":"Treatment of children with intestinal failure: intestinal rehabilitation, home parenteral nutrition or small intestine transplantation?","volume":"158","author":"Neelis EG","year":"2014","journal-title":"Ned Tijdschr 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