{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:48:46Z","timestamp":1786978126563,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,3,16]],"date-time":"2025-03-16T00:00:00Z","timestamp":1742083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["aspenjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Intestinal failure\u2013associated liver disease (IFALD) is a major complication of chronic intestinal failure. Few data exist about hepatic monitoring of IFALD using the liver stiffness measurement. The aim of this study was to provide a descriptive analysis of IFALD and its prevalence in a tertiary center and to determine the IFALD risk factors and high liver stiffness measurement values using FibroScan.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Adult patients with chronic intestinal failure treated with home parenteral nutrition and followed in a tertiary center with no underlying liver disease and at least one liver stiffness measurement record were included between January 1, 2007, and June 6, 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Eighty\u2010nine patients were included from this cohort of 145 patients. The prevalence of IFALD was 34%. A total of 14% had a liver stiffness measurement &gt;10\u2009kPa, and 49% had a liver stiffness measurement &lt;5\u2009kPa. In multivariate analysis, IFALD was positively associated with the use of a customized admixture (odds ratio [OR]\u2009=\u20097.04; 95% CI, 1.44\u201343.64;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.017) and negatively associated with the colon in continuity (OR\u2009=\u20090.25; 95% CI, 0.07\u20130.87;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.029). No significant association was observed between liver stiffness measurement values and IFALD.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The prevalence of IFALD was low in our study. Absence of the colon and the use of a customized admixture were risk factors for IFALD. Liver stiffness measurement was abnormal in 51% of cases. A long\u2010term follow\u2010up of this cohort will help to assess the prognostic relevance of IFALD and liver stiffness measurement in these patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jpen.2746","type":"journal-article","created":{"date-parts":[[2025,3,16]],"date-time":"2025-03-16T08:19:26Z","timestamp":1742113166000},"page":"507-516","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Intestinal failure\u2013associated liver disease in adult patients with chronic intestinal failure receiving home parenteral nutrition: A descriptive cohort study"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-5554-1248","authenticated-orcid":false,"given":"Sarah","family":"Frezet","sequence":"first","affiliation":[{"name":"Gastroenterology Department, CHU de Bordeaux, Centre Medico\u2010chirurgical Magellan, H\u00f4pital Haut\u2010L\u00e9v\u00eaque Universit\u00e9 de Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Hermabessi\u00e8re","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, CHU de Bordeaux, Centre Medico\u2010chirurgical Magellan, H\u00f4pital Haut\u2010L\u00e9v\u00eaque Universit\u00e9 de Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurianne","family":"Kerlogot","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, CHU de Bordeaux, Centre Medico\u2010chirurgical Magellan, H\u00f4pital Haut\u2010L\u00e9v\u00eaque Universit\u00e9 de Bordeaux Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Wilsius","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, CHU de Bordeaux, Centre Medico\u2010chirurgical Magellan, H\u00f4pital Haut\u2010L\u00e9v\u00eaque Universit\u00e9 de Bordeaux Bordeaux 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