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We report a case of a 29\u2010year\u2010old primigravid woman with Crohn's disease who required chronic PN. Despite these complexities, her pregnancy was managed successfully with tailored PN adjustments. She developed intrahepatic cholestasis of pregnancy at 38 weeks and delivered a healthy, full\u2010term newborn. Meticulous planning and individualized nutrition management are crucial in navigating the complexities of PN during pregnancy, demonstrating the potential for successful outcomes with strategic and personalized interventions.<\/jats:p>","DOI":"10.1002\/jpen.2758","type":"journal-article","created":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T03:55:11Z","timestamp":1743566111000},"page":"528-533","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Managing pregnancy with long\u2010term parenteral nutrition: A case report and review of the literature"],"prefix":"10.1002","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4010-7545","authenticated-orcid":false,"given":"Muhammad","family":"Shahzil","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Penn State Health Milton S. 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