{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T08:54:56Z","timestamp":1781513696511,"version":"3.54.1"},"reference-count":36,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["#314479\/2023\u20106"],"award-info":[{"award-number":["#314479\/2023\u20106"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pulsed electromagnetic field (PEMF) therapy, renowned for its immunomodulatory effects and established efficacy in orthopedics, shows promise for managing peri\u2010implantitis by reducing soft tissue inflammation and marginal bone loss. This study aimed to compare the long\u2010term clinical and radiographic outcomes of nonsurgical peri\u2010implantitis treatment with and without PEMF therapy. This multicenter retrospective\u2010prospective analysis combined data from two centers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty\u2010three patients, with a total of 47 implants displaying peri\u2010implantitis diagnosed with pocket probing depths (PD) of 6\u20138\u00a0mm with bleeding on probing (BoP) and crestal bone loss ranging from 3\u20135\u00a0mm, completed this study. Nonsurgical mechanical debridement was conducted, and a novel healing abutment integrating active (25 test) or inactive (22 control) PEMF was installed. The abutments with PEMF provided an exposure ratio of 1\/500\u20131\/5000, an intensity of 0.05\u20130.5\u00a0mT, and a frequency of 10\u201350\u00a0kHz for 30 days. Patients were evaluated at baseline (T0), 3 months (T1), and 20 months (T2), assessing plaque index (PI), BoP, PD, recession depth (REC), suppuration (SUP), and radiographically measured vertical bone loss (VBL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Follow\u2010up assessments revealed a significantly lower mean of PD at the deepest site and BoP in the test group after a mean time of 20 months compared to the control (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). Furthermore, within the test group, PD at the deepest site and mean PD decreased significantly between T0 and T2 (7.1\u00a0\u00b1\u00a01.5\u00a0mm to 4.6\u00a0\u00b1\u00a00.73\u00a0mm, 5.3\u00a0\u00b1\u00a01.3\u00a0mm to 3.7\u00a0\u00b1\u00a01.2\u00a0mm, respectively;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). A decrease in mean PD was also observed in the control group for the latter (6.8\u00a0\u00b1\u00a01.1\u00a0mm to 5.4\u00a0\u00b1\u00a01.4\u00a0mm;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.05). Although not significant, a positive trend was observed for VBL after 1 year in the test group compared to the control (0.2\u00a0\u00b1\u00a00.4\u00a0mm vs. \u22120.3\u00a0\u00b1\u00a00.11\u00a0mm). The clinical end point (PD\u00a0&lt;\u00a05\u00a0mm, absence of BoP and\/or SUP, and no bone loss) was 54.54% and 68% for the control and test group, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These findings suggest that focused PEMF therapy could offer a nonsurgical solution for peri\u2010implantitis that can achieve the clinical goals. Nevertheless, larger samples and longer follow\u2010ups are needed to understand its long\u2010term benefits and limitations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>The nonsurgical treatments of dental implant infections often result in a limited impact of the inflammation, reducing the bleeding on the gums around the implants. To overcome this limitation during treatment, this study evaluated the pulsed electromagnetic field (PEMF) employed in several medical fields, such orthopedics, for its immunomodulatory and bone\u2010healing properties. A small device was coupled with the dental implant to release the pulse. The PEMF associated with nonsurgical debridement in the gums around diseased implants demonstrated that PEMF therapy improved the healthy status of these implants 12\u201326 months after treatment. The findings suggest potential clinical benefits of noninvasive PEMF in treating diseased implants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.11384","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T09:09:28Z","timestamp":1754125768000},"page":"646-657","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pulsed electromagnetic field therapy on nonsurgical treatment of peri\u2010implantitis: 12\u201326 months follow\u2010up"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5500-7961","authenticated-orcid":false,"given":"Yaniv","family":"Mayer","sequence":"first","affiliation":[{"name":"Department of Periodontology Rambam Health Care Campus  Haifa Israel"},{"name":"Technion Israel Institute of Technology Rappaport Faculty of Medicine  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0429-2883","authenticated-orcid":false,"given":"Eran","family":"Gabay","sequence":"additional","affiliation":[{"name":"Department of Periodontology Rambam Health Care Campus  Haifa Israel"},{"name":"Technion Israel Institute of Technology Rappaport Faculty of Medicine  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amin","family":"Younis","sequence":"additional","affiliation":[{"name":"Department of Periodontology Rambam Health Care Campus  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8736-9753","authenticated-orcid":false,"given":"Ofir","family":"Ginesin","sequence":"additional","affiliation":[{"name":"Department of Periodontology Rambam Health Care Campus  Haifa Israel"},{"name":"Technion Israel Institute of Technology Rappaport Faculty of Medicine  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael S.","family":"Siroma","sequence":"additional","affiliation":[{"name":"Department of Periodontology Dental Research Division Guarulhos University  Guarulhos SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shlomo","family":"Barak","sequence":"additional","affiliation":[{"name":"Department of Periodontology Dental Research Division Guarulhos University  Guarulhos SP Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ido","family":"Georgy","sequence":"additional","affiliation":[{"name":"Department of Periodontology Rambam Health Care Campus  Haifa Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoni","family":"Friedlander","sequence":"additional","affiliation":[{"name":"Department of Periodontology Rambam Health Care Campus  Haifa 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