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Thus, control of gingival inflammation is essential for the primary prevention of periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>The clinical characteristics common to dental plaque\u2013induced inflammatory gingival conditions include: a) clinical signs and symptoms of inflammation that are confined to the gingiva: b) reversibility of the inflammation by removing or disrupting the biofilm; c) the presence of a high bacterial plaque burden to initiate the inflammation; d) systemic modifying factors (e.g., hormones, systemic disorders, drugs) which can alter the severity of the plaque\u2010induced inflammation and; e) stable (i.e., non\u2010changing) attachment levels on a periodontium which may or may not have experienced a loss of attachment or alveolar bone. The simplified taxonomy of gingival conditions includes: 1) introduction of the term \u201cincipient gingivitis;\u201d 2) a description of the extent and severity of gingival inflammation; 3) a description of the extent and severity of gingival enlargement and; 4) a reduction of categories in the dental plaque\u2013induced gingival disease taxonomy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Dental plaque\u2013induced gingival inflammation is modified by various systemic and oral factors. The appropriate intervention is crucial for the prevention of periodontitis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.17-0095","type":"journal-article","created":{"date-parts":[[2018,6,21]],"date-time":"2018-06-21T06:43:40Z","timestamp":1529563420000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":214,"title":["Dental plaque\u2013induced gingival conditions"],"prefix":"10.1002","volume":"89","author":[{"given":"Shinya","family":"Murakami","sequence":"first","affiliation":[{"name":"Osaka University Graduate School of Dentistry\u2010Department of Periodontology  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian L.","family":"Mealey","sequence":"additional","affiliation":[{"name":"Department of Periodontics The University of Texas Health Science Center at San Antonio  San Antonio TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Mariotti","sequence":"additional","affiliation":[{"name":"Division of Periodontology, College of Dentistry The Ohio State University  Columbus OH USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain L.C.","family":"Chapple","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Birmingham School of Dentistry  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,6,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.16-0517"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.54"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2017.02.006"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00823.x"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/annals.1999.4.1.7"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1965.36.3.177"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12382"},{"key":"e_1_2_12_9_1","volume-title":"Periodontal Disease in Adults, United States 1960\u20131962","author":"U.S. Public Health Service NCHS","year":"1965"},{"key":"e_1_2_12_10_1","volume-title":"Periodontal Diseases and Oral Hygiene Among Children, United States","author":"U.S. Public Health Service NCHS","year":"1972"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01473.x"},{"key":"e_1_2_12_12_1","volume-title":"Oral Health of United States Adults; 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