{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:34:17Z","timestamp":1792456457707,"version":"4.5.0"},"reference-count":24,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Evidence exists on the clinical efficacy and safety of periodontally accelerated osteogenic orthodontics (PAOO) with \u201cPiezocision\u201d\u2014a minimally invasive, flapless alternative to corticotomy for alveolar bone augmentation. Allograft has been extensively studied for alveolar bone augmentation in Piezocision; however, the use of deproteinized bovine bone mineral with 10% collagen (DBBM\u2010C) in Piezocision for PAOO has not been investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study is a prospective, observational, cohort study of 19 patients of Angle Class I malocclusion with a total of 692 teeth assessed for maintenance of health of the periodontal attachment apparatus. Patient\u2010centered pain, sensitivity, and satisfaction outcomes, digital photographs and radiographs, and changes in probing depth, clinical attachment level, width of keratinized tissue, percussion sensitivity, pulp vitality tests, radiographic pathology, and root\u2010crown\u2010ratio were all recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall treatment was significantly faster (5 to 7\u00a0days between clear aligner tray changes), periodontal parameters remained stable, and alveolar bone loss was not observed. Visual analog score for healing, sensitivity\/duration, bleeding\/duration, swelling\/duration, appearance, and inflammation, demonstrated no significant differences between DBBM\u2010C and control (no bone graft) groups. Patient\u2010centered outcomes revealed high levels of satisfaction with Piezocision. Piezocision\u2010treated teeth with DBBM\u2010C tended to exhibit less root resorption, although it was not statistically significant (<jats:italic>P\u00a0<\/jats:italic>=\u00a00.074).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the limits of the study, our results show that the use of DBBM\u2010C with piezosurgically enhanced orthodontics is effective and safe. This study was not designed to demonstrate equivalence with other materials that might be used in Piezocision. To understand whether there is an advantage to using DBBM\u2010C, additional studies may be required.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.18-0737","type":"journal-article","created":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T05:39:21Z","timestamp":1553837961000},"page":"1106-1115","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["The clinical efficacy of deproteinized bovine bone mineral with 10% collagen in conjunction with localized piezosurgical decortication enhanced orthodontics: A prospective observational study"],"prefix":"10.1002","volume":"90","author":[{"given":"Takanari","family":"Miyamoto","sequence":"first","affiliation":[{"name":"Department of Periodontics School of Dentistry Creighton University  Omaha NE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Lang","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Creighton University  Omaha NE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shakeel","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Creighton University  Omaha NE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kota","family":"Kumagai","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Creighton University  Omaha NE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha E.","family":"Nunn","sequence":"additional","affiliation":[{"name":"Department of Periodontics School of Dentistry Creighton University  Omaha NE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,25]]},"reference":[{"key":"e_1_2_8_2_1","first-page":"342","article-title":"Piezocision: a minimally invasive, periodontally accelerated orthodontic tooth movement procedure","volume":"30","author":"Dibart S","year":"2009","journal-title":"Compend Contin Educ Dent"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.04.124"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1097\/00003086-198911000-00046","article-title":"The biology of fracture healing. 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