{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T07:12:45Z","timestamp":1787987565077,"version":"build-2784847793"},"reference-count":50,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,8,11]],"date-time":"2020-08-11T00:00:00Z","timestamp":1597104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The association between low bone mineral density (BMD) and periodontitis in perimenopausal women is controversial. The purpose of this study was to determine whether osteoporosis or osteopenia is associated with periodontal disease in a population of adult women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A sample of over\u201045\u2010year\u2010old women with or without low BMD underwent lumbar spine and hip bone densitometry and a complete periodontal examination. The extent\/severity or absence of periodontal disease was noted using two different case definitions. Data were gathered on socio\u2010economic status, medication history, systemic co\u2010morbidities, alcohol or tobacco use as well as serum levels of calcium and vitamin D.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One hundred seventy three women aged between 45 and 72 years old were recruited with a mean age of 57.8 years. One hundred and three had decreased BMD (61 with osteoporosis and 42 with osteopenia) and 70 were healthy. Moderate or severe periodontitis was present in 52.6% of the women. Multivariate analysis showed a clear association between low BMD and periodontitis, but only in women above 58 years old and independent of tobacco consumption or oral hygiene.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this sample of generally healthy perimenopausal women, low BMD was associated with clinical attachment level (CAL). Women over 58 years old with decreased BMD presented with a higher mean percentage of sites with CAL \u2265 4\u00a0mm as well as CAL \u2265 6\u00a0mm when compared to controls, independent of active smoking status or poor oral hygiene.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.20-0029","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T08:21:40Z","timestamp":1595838100000},"page":"95-103","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Association between low bone mineral density and periodontitis in generally healthy perimenopausal women"],"prefix":"10.1002","volume":"92","author":[{"given":"Jos\u00e9 Antonio","family":"Gil\u2010Montoya","sequence":"first","affiliation":[{"name":"Biosanitary Institute of Granada (ibs.GRANADA) University Hospitals of Granada\u2010University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Macarena","family":"Garrido\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Granada School of Dentistry Granada University  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roc\u00edo","family":"Barrios\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Biosanitary Institute of Granada (ibs.GRANADA) University Hospitals of Granada\u2010University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Ramos\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Biosanitary Institute of Granada (ibs.GRANADA) University Hospitals of Granada\u2010University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Lenouvel","sequence":"additional","affiliation":[{"name":"Biosanitary Institute of Granada (ibs.GRANADA) University Hospitals of Granada\u2010University of Granada  Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Montes\u2010Castillo","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition Jaen General Hospital  Ja\u00e9n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Jos\u00e9","family":"Mart\u00ednez\u2010Ram\u00edrez","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Nutrition Jaen General Hospital  Ja\u00e9n Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,8,11]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"261","article-title":"Diagnosis and management of osteoporosis","volume":"92","author":"Jeremiah MP","year":"2015","journal-title":"Am Fam Physician"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-013-0136-1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1513724"},{"key":"e_1_2_9_5_1","first-page":"515","article-title":"Clinical practice guidelines for posmenopausal, glucocorticoid\u2010induced and male osteoporosis. 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