{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T19:30:21Z","timestamp":1789241421103,"version":"build-2803163510"},"reference-count":50,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,8,30]],"date-time":"2020-08-30T00:00:00Z","timestamp":1598745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study was conducted to assess the clinical, immunological, and patient\u2010centered outcomes of microcurrent electrotherapy on palatal wound healing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a parallel, double\u2010masked randomized clinical trial, in which 53 patients with ridge preservation indications were selected and randomly assigned to one of two groups. In the control (sham) group (n\u00a0=\u00a027), palatal wounds, after free gingival grafts (FGG) harvest, received sham application of electrotherapy. In the test (electrotherapy treatment [EE]) group (n\u00a0=\u00a026), palatal wounds, after FGG harvest, received application of microcurrent electrotherapy protocol. Clinical parameters, patient\u2010centered outcomes, and inflammatory markers were evaluated, up to 90 days postoperatively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The EE group achieved earlier wound closure (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;0.001) and epithelialization (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;0.05;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.03) at 7 and 14 days after harvest when compared with the sham group. Painful symptomatology was reported less frequently in the EE group than in the sham group at 3\u2010day follow\u2010up (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.008). Likewise, an improvement in Oral Health Impact Profile was reported 2 days after the procedure by the EE group (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.04). In addition, favorable modulation of inflammatory wound healing markers occurred when electrotherapy was applied.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within the limits of the present study, it can be concluded that the use of a low\u2010intensity electrotherapy protocol may accelerate palatal wound healing and decrease patient discomfort after FGG harvest.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.20-0122","type":"journal-article","created":{"date-parts":[[2020,8,12]],"date-time":"2020-08-12T03:25:30Z","timestamp":1597202730000},"page":"244-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Microcurrent electrotherapy improves palatal wound healing: Randomized clinical trial"],"prefix":"10.1002","volume":"92","author":[{"given":"Manuela Maria 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