{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:41:10Z","timestamp":1789594870700,"version":"build-2803163510"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,11,15]],"date-time":"2021-11-15T00:00:00Z","timestamp":1636934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Xenogeneic matrices (XMs) have been increasingly used for root coverage procedures. This study compared the use of two types of XM (collagen matrix [CM] and xenogeneic acellular dermal matrix [XDM]) associated with the coronally advanced flap technique (CAF) to treat single gingival recessions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy\u2010five patients presenting single RT1 gingival recession were treated by CAF (control group, <jats:italic>n<\/jats:italic>\u00a0=\u00a025), CAF+CM (test group 1, <jats:italic>n<\/jats:italic>\u00a0=\u00a025), or CAF+XDM (test group 2, <jats:italic>n<\/jats:italic>\u00a0=\u00a025) and completed 6\u2010month follow\u2010up. Clinical, patient\u2010centered, and esthetic assessments were performed and intra\u2010 and intergroup differences were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 6 months, the mean recession reduction for CAF, CAF+CM, and CAF+XDM was 2.4 \u00b1 0.8\u00a0mm, 2.4 \u00b1 0.9\u00a0mm and 2.1 \u00b1 0.8\u00a0mm, respectively (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). The corresponding mean percentage of root coverage was 78.9% \u00b1 26.2% for CAF, 78.0% \u00b1 28.5% for CAF+CM, and 65.6% \u00b1 26.9% for CAF+XDM (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Dentin hypersensitivity and esthetic conditions showed significantly improvements in all groups. Test groups presented significant gains in gingival thickness (GT; CAF+CM: 0.4 \u00b1 0.3\u00a0mm; CAF+XDM: 0.4 \u00b1 0.2\u00a0mm) compared to the control group (CAF: 0.0 \u00b1 0.1\u00a0mm; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The CAF, CAF+CM, and CAF+XDM treatments each provided similar results in the treatment of single gingival recessions. The addition of either CM or XDM to CAF increases the GT.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.21-0212","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T17:31:05Z","timestamp":1633109465000},"page":"709-720","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial"],"prefix":"10.1002","volume":"93","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9468-0729","authenticated-orcid":false,"given":"Mauro Pedrine","family":"Santamaria","sequence":"first","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"},{"name":"College of Dentistry\u2013Lexington University of Kentucky  Lexington Kentucky USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Rossato","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela Maria Viana","family":"Miguel","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuela Bafini","family":"Fonseca","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristhian Reynaldo Gomez","family":"Bautista","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea Carvalho","family":"de Marco","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingrid Fernandes","family":"Mathias\u2010Santamaria","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"},{"name":"Division of Operative Dentistry Department of General Dentistry University of Maryland School of Dentistry  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00eds Fernanda","family":"Ferreira Ferraz","sequence":"additional","affiliation":[{"name":"Division of Periodontics Institute of Science and Technology S\u00e3o Jos\u00e9 dos Campos S\u00e3o Paulo State University (Unesp)  S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,15]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1999.70.9.1064"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01267.x"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12182"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12186"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12248"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2011.110215"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12019"},{"issue":"3","key":"e_1_2_9_9_1","first-page":"259","article-title":"Effect of xenogeneic dermal matrix associated with coronally advanced flap in the treatment of single gingival recessions: a case series","volume":"23","author":"Ferraz LFF","year":"2021","journal-title":"J Int Acad Periodontol"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090698"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2014.130693"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12115"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-020-03280-x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000000524"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10024-2052"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2020.07.002"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2016.150676"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12337"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12547"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13031"},{"issue":"1","key":"e_1_2_9_21_1","first-page":"32","article-title":"Long\u2010term results after treatment of multiple adjacent gingival recessions with the modified coronally advanced tunnel and a porcine acellular dermal matrix","volume":"52","author":"Cosgarea R","year":"2021","journal-title":"Quintessence Int"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-021-03879-8"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19-0107"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13196"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01732.x"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.01039.x"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2016.160391"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-015-1614-1"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12714"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12907"},{"issue":"4","key":"e_1_2_9_31_1","first-page":"229","article-title":"Problems and proposals for recording gingivitis and plaque","volume":"25","author":"Ainamo J","year":"1975","journal-title":"Int Dent J"},{"issue":"2","key":"e_1_2_9_32_1","first-page":"107","article-title":"Gingival sulcus bleeding\u2010a leading symptom in initial gingivitis","volume":"15","author":"M\u00fchlemann HR","year":"1971","journal-title":"Helv Odontol Acta"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19\u20100436"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.090366"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.110660"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.080565"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-016-1757-8"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2015.130674"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.10.1350"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/jerd.12122"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2017.170126"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0619"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12211"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13229"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.18-0201"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2005.76.10.1729"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2012.120479"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0757.2011.00434.x"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/JPER.21-0212","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/JPER.21-0212","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/JPER.21-0212","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T14:03:02Z","timestamp":1760882582000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/JPER.21-0212"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,15]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10.1002\/JPER.21-0212"],"URL":"https:\/\/doi.org\/10.1002\/jper.21-0212","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,15]]},"assertion":[{"value":"2021-04-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}