{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T17:35:51Z","timestamp":1790444151456,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this study was to evaluate the association between systemic non\u2010communicable diseases (NCDs; including lung, kidney, mental and cardiovascular diseases, arthritis, cancer and spinal problems), common risk factors, and tooth loss (TL), as an endpoint of prevalent oral NCDs (periodontitis and caries).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 60,271 noninstitutionalized adults (\u226530 years) were evaluated, using data from the 2019 Brazilian National Health Survey. Negative binomial regressions were performed, adjusting for sex, age, ethnicity, educational attainment, oral hygiene, risk factors for periodontitis and caries (diabetes, smoking, and a cariogenic diet). The dependent variable was TL expressed as a numerical value.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Diabetes, current smoking and a frequent cariogenic diet were significantly associated with TL\u2013Incidence Rate Ratio (IRR [95% CI]): 1.11 (1.08 to 1.14), 1.28 (1.25 to 1.31), and 0.97 (0.94 to 0.99), respectively. Significant associations were observed for TL and all assessed NCDs, except kidney diseases, cancer and musculoskeletal diseases related to work, with IRR ranging from 1.06 for hypertension and asthma to 1.16 for rheumatoid arthritis. Regular consumption (4 to 7\u00a0d\/wk) of vegetables, fruits and beef; alcohol up to 8 doses\/wk; and physical exercise were associated with a lower IRR for TL (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Obesity, but not overweight, was associated with increased TL (1.05 [1.03 to 1.07]). Smoking, hypertension, arthritis, other mental diseases and spinal problems further increased the IRR for TL in individuals with diabetes (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>We conclude that certain chronic systemic conditions are associated with TL in Brazilian adults. This is likely because of shared risk factors; however, causal associations cannot be examined in this cross\u2010sectional dataset.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.21-0433","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:59:00Z","timestamp":1639443540000},"page":"1141-1149","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Association between tooth loss, chronic conditions, and common risk factors: Results from the 2019 Brazilian Health Survey"],"prefix":"10.1002","volume":"93","author":[{"given":"Tayse Caroline Cunha","family":"de Medeiros","sequence":"first","affiliation":[{"name":"Department of Stomatology Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra","family":"Areas e Souza","sequence":"additional","affiliation":[{"name":"Department of Stomatology Universidade Federal do Paran\u00e1  Curitiba Brazil"},{"name":"Department of Specific Training Universidade Federal Fluminense  Nova Friburgo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo Coelho","family":"Prates","sequence":"additional","affiliation":[{"name":"Postgraduate Program in Health and Environment Universidade da Regi\u00e3o de Joinville \u2010 Univille  Joinville Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iain","family":"Chapple","sequence":"additional","affiliation":[{"name":"Periodontal Research Group, Institute of Clinical Sciences, College of Medical and Dental Sciences University of Birmingham, and Birmingham Community Healthcare Foundation NHS Trust  Birmingham UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6071-553X","authenticated-orcid":false,"given":"Joao Paulo","family":"Steffens","sequence":"additional","affiliation":[{"name":"Department of Stomatology Universidade Federal do Paran\u00e1  Curitiba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,1,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910708601205"},{"key":"e_1_2_9_3_1","volume-title":"Time to Take Gum Disease Seriously: The Societal and Economic Impact of Periodontitis","author":"The Economist Intelligence Unit","year":"2021"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513490168"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17176258"},{"issue":"18","key":"e_1_2_9_6_1","first-page":"S95","article-title":"Global epidemiology of dental caries and severe periodontitis\u2013A comprehensive review","volume":"44","author":"Frencken JE","year":"2017","journal-title":"J Clin Periodontol"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034514552491"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515573272"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12685"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0721"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.13.4.547"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2012-202701"},{"key":"e_1_2_9_13_1","first-page":"1","article-title":"Common risk factors for major noncommunicable disease, a systematic overview of reviews and commentary: the implied potential for targeted risk reduction","volume":"15","author":"Peters REN","year":"2019","journal-title":"Ther Adv Chronic Dis"},{"key":"e_1_2_9_14_1","volume-title":"The World Oral Health Report 2003: Continuous Improvement of Oral Health in the 21st Century\u2013The Approach of the WHO Global Oral Health Programme","author":"Petersen PE","year":"2003"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345960750120101"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/eos.12528"},{"key":"e_1_2_9_17_1","volume-title":"White Paper on Prevention and Management of Periodontal Diseases for Oral Health and General Health","author":"Herrera D","year":"2018"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01173.x"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13414"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0528.2000.028006399.x"},{"key":"e_1_2_9_21_1","volume-title":"2019 Health National Survey. 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