{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T10:08:14Z","timestamp":1780049294618,"version":"3.53.1"},"reference-count":34,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The purpose of this study was to evaluate the results of adjunctive Er,Cr:YSGG laser therapy with scaling and root planing (SRP) as compared with SRP alone in the treatment of moderate to severe periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fifteen adults (aged 27 to 65 years) with 90 nonadjacent sites probing \u2265 5\u00a0mm were treated in split\u2010mouth design with SRP and laser therapy versus SRP alone. Probing pocket depth (PPD), gingival recession (GR), clinical attachment level (CAL), plaque, and bleeding on probing were collected at baseline, 1, 3, 6, 9, and 12 months. Patient reported outcomes were measured to assess pain, sensitivity, and satisfaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinical improvements were similar for test and control sites with no statistically significant difference. At 12 months, the average PPD reduced from 6.1 to 4.2\u00a0mm for test and 6.2 to 4.3\u00a0mm for control sites. GR increased by 0.4\u00a0mm at test and control sites. CAL increased from 6.8 to 5.3\u00a0mm for test and 6.9 to 5.5\u00a0mm for control sites. Clinical outcomes were stratified by baseline PPD ( =\u00a05,\u00a0=\u00a06 and \u22657\u00a0mm) and analyzed for number of sites that reduced (\u22644\u00a0mm). No significant difference was observed when the baseline PPD was 5 or 6\u00a0mm. Test sites with baseline PPD \u22657\u00a0mm demonstrated a statistically significant difference in the percentage of reduced sites when compared with controls at nine (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.001) and 12 months (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.044).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Adjunctive Er,Cr:YSGG laser therapy with SRP provides similar clinical improvement in the treatment of moderate\u2010severe periodontitis as SRP alone and may offer some advantage for deeper (\u22657\u00a0mm) pockets.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.21-0443","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T11:50:04Z","timestamp":1646308204000},"page":"1314-1324","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Clinical evaluation of Er,Cr:YSGG laser therapy used as an adjunct to non\u2010surgical treatment of periodontitis: Twelve\u2010month results from a pilot study"],"prefix":"10.1002","volume":"93","author":[{"given":"Perry R.","family":"Klokkevold","sequence":"first","affiliation":[{"name":"Section of Periodontics UCLA School of Dentistry  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arianna","family":"Damian","sequence":"additional","affiliation":[{"name":"Section of Periodontics, Private Practice UCLA School of Dentistry  Brentwood CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlene","family":"Pham","sequence":"additional","affiliation":[{"name":"Section of Periodontics, Private Practice UCLA School of Dentistry  Menifee CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay M.","family":"Mallya","sequence":"additional","affiliation":[{"name":"Section of Oral and Maxillofacial Radiology UCLA School of Dentistry  Los Angeles CA 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