{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T13:42:48Z","timestamp":1791985368961,"version":"4.4.0"},"reference-count":78,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The objective of this systematic review was to shed light on the importance of surgical\u2010 and implant\u2010related factors on the onset\/progression of peri\u2010implant diseases. This systematic review provides an evidence\u2010based overview on the prevention of peri\u2010implant diseases for the Academy of Osseointegration (AO)\/American Academy of Periodontology (AAP) Consensus Conference held in August 14\u201316, 2024 in Oakbrook, IL, USA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Systematic screening of electronic sources was performed to identify clinical studies reporting on the impact of surgical\u2010 and implant\u2010related factors on peri\u2010implant diseases. To fulfil the inclusion criteria, a composite clinical and radiographic case definition for peri\u2010implant mucositis and\/or peri\u2010implantitis had to be reported. Prevalence or incidence (%) of peri\u2010implant diseases was extracted at patient\u2010 and implant\u2010level. Moreover, odds\/hazard ratios were collected to explore potential associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 34 articles were included in the qualitative synthesis. Of these, 21 explored surgical\u2010related factors (\n                      <jats:italic>N<\/jats:italic>\n                      <jats:sub>patients\u00a0<\/jats:sub>\n                      =\u00a02752,\n                      <jats:italic>N<\/jats:italic>\n                      <jats:sub>implants\u00a0<\/jats:sub>\n                      =\u00a07591), while 13 reported implant\u2010related factors (\n                      <jats:italic>N<\/jats:italic>\n                      <jats:sub>patients\u00a0<\/jats:sub>\n                      =\u00a01192,\n                      <jats:italic>N<\/jats:italic>\n                      <jats:sub>implants\u00a0<\/jats:sub>\n                      =\u00a04072). Given the high heterogeneity across the studies, only qualitative assessment was performed. Clinical evidence proved that surgical\u2010related factors, in particular inadequate implant position and, to a lower extent, implants placed in regenerated bone, are more prone to exhibit peri\u2010implantitis, but not peri\u2010implant mucositis. With regards to specific implant\u2010related factors, insufficient evidence, did not allow for exploring specific associations with the onset\/progression of peri\u2010implant diseases. However, it was found that a short distance from the prosthetic margin to crestal bone during implant placement may be a predisposing factor for peri\u2010implantitis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Clinical evidence linking surgical\u2010 and implant\u2010related factors and peri\u2010implant diseases is sparsely reported in the literature. Nevertheless, it appears that implant malposition plays a crucial role on the onset\/progression of peri\u2010implantitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain Language Summary<\/jats:title>\n                    <jats:p>The objective of this systematic review was to shed light on the importance of surgical\u2010and implant\u2010related factors on the onset\/progression of peri\u2010implant diseases. Overall, 33 articles were included in the qualitative synthesis. Of these, 21 explored surgical\u2010related factors. Given the high heterogeneity across the studies, only qualitative assessment was performed. Clinical evidence proved that surgical\u2010related factors, in particular inadequate implant position and, to a lower extent, implants placed in regenerated bone, are more prone to exhibit peri\u2010implantitis, but not peri\u2010implant mucositis. With regards to specific implant\u2010related factors, insufficient evidence, did not allow for exploring specific associations with the onset\/progression of peri\u2010implant diseases. However, it was found that a short distance from the prosthetic margin to crestal bone during implant placement may be a predisposing factor for peri\u2010implantitis. All in all, implant malposition plays a crucial role on the onset\/progression of peri\u2010implantitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.24-0083","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T12:10:06Z","timestamp":1749471006000},"page":"542-561","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Surgical\u2010 and implant\u2010related factors and onset\/progression of peri\u2010implant diseases: An AO\/AAP systematic review"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8292-1927","authenticated-orcid":false,"given":"Alberto","family":"Monje","sequence":"first","affiliation":[{"name":"Department of Periodontology and Oral Medicine University of Michigan  Ann Arbor Michigan USA"},{"name":"Department of Periodontology Universitat Internacional de Catalunya  Barcelona Spain"},{"name":"Department of Periodontology University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5347-6577","authenticated-orcid":false,"given":"Shayan","family":"Barootchi","sequence":"additional","affiliation":[{"name":"Department of Periodontology Harvard School of Dental Medicine  Boston USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Rosen","sequence":"additional","affiliation":[{"name":"Department of Periodontology Rutgers University School of Dental Medicine  Piscataway USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Medicine University of Michigan  Ann Arbor Michigan 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