{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T22:02:00Z","timestamp":1791237720959,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T00:00:00Z","timestamp":1717372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Backgound<\/jats:title><jats:p>The aim of this randomized controlled trial was to assess clinical and patient\u2010reported outcomes of subgingival instrumentation (SI) with adjunctive use of erythritol airflowing (EAF)\u00a0compared to\u00a0SI alone in the treatment\u00a0of\u00a0periodontitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010six participants with Stage III\/IV periodontitis requiring nonsurgical periodontal treatment were randomly allocated into two treatment groups: SI with EAF or SI alone. Clinical parameters of percentage of probing pocket depths (PPDs) of \u22655\u00a0mm, full mouth bleeding and plaque scores (FMBS and FMPS), and PPD values were recorded at baseline, and at 3 and 6 months posttreatment.\u00a0A visual analogue scale was used to evaluate\u00a0postoperative participants\u2019 perception of pain, swelling, bleeding, bruising, and root sensitivity.\u00a0The impact of periodontal treatment on\u00a0quality of life\u00a0was assessed using the General Oral Health Assessment Index (GOHAI) at six months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 26 participants with Stage III\/IV periodontitis completed the 6\u2010month follow\u2010up. SI with or without EAF resulted in a statistically significant reductions in the FMBS, FMPS, PPDs, and percentage of PPDs of \u22655\u00a0mm at the 3\u2010 and 6\u2010month follow\u2010up visits. There was no statistically significant difference between the two treatment groups for any time interval. Participants receiving SI\/EAF exhibited a higher reduction in FMBS compared to those in SI alone group at 3 (SI\/EAF: 19.4\u00a0\u00b1\u00a011.9, SI alone:\u00a030.1\u00a0\u00b1\u00a020.5; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.12) and 6 months (SI\/EAF: 14.3\u00a0\u00b1\u00a09.6, SI alone: 24.5\u00a0\u00b1\u00a018.2; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.09). A lower percentage of sites with deep PPDs (\u22655\u00a0mm) was also noted amongst participants in the SI\/EAF group compared to SI alone at 3 months (SI\/EAF: 14.3\u00a0\u00b1\u00a014.1, SI alone:\u00a019.2\u00a0\u00b1\u00a020.3; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.48) and 6 months (SI\/EAF: 8.3\u00a0\u00b1\u00a010.0, SI alone: 15.4\u00a0\u00b1\u00a017.4; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.22). Patient\u2010reported outcomes showed no significant differences between the two treatment groups, except in the psychosocial domain of the GOHAI at 6 months favoring the SI\/EAF group (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.03).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the limitations of the study, the adjunctive use of EAF in addition to SI in the treatment of Stage III\/IV\u00a0periodontitis\u00a0did not result in a significant improvement in clinical parameters. Limited improvement in the QoL with EAF could be achieved.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.24-0099","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T21:39:32Z","timestamp":1717450772000},"page":"1048-1059","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Airflowing as an adjunctive treatment for periodontitis: A randomized controlled trial"],"prefix":"10.1002","volume":"95","author":[{"given":"Salem","family":"Alsuwaidi","sequence":"first","affiliation":[{"name":"Mohammed Bin Rashid University of Medicine and Health Sciences Hamdan Bin Mohammed College of Dental Medicine, Dubai Health  Dubai United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aisha","family":"Almatrooshi","sequence":"additional","affiliation":[{"name":"Dubai Health  Dubai United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maanas","family":"Shah","sequence":"additional","affiliation":[{"name":"Mohammed Bin Rashid University of Medicine and Health Sciences Hamdan Bin Mohammed College of Dental Medicine, Dubai Health  Dubai United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abeer","family":"Hakam","sequence":"additional","affiliation":[{"name":"Mohammed Bin Rashid University of Medicine and Health Sciences Hamdan Bin Mohammed College of Dental Medicine, Dubai Health  Dubai United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Tawse\u2010Smith","sequence":"additional","affiliation":[{"name":"Sir John Walsh Research Institute, Faculty of Dentistry University of Otago  Dunedin New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nabeel H. 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