{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,3]],"date-time":"2026-04-03T00:26:35Z","timestamp":1775175995620,"version":"3.50.1"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>To compare bone regeneration and dimensional alteration of alveolar ridge at intact and damaged extraction sockets after alveolar ridge preservation (ARP) and implant placement versus unassisted socket healing followed by guided bone regeneration (GBR) with simultaneous implant placement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In 6 beagle dogs, 3 types of extraction sockets in the mandible were created: (1) intact sockets, (2) 1\u2010wall defect sockets and (3) 2\u2010wall defect sockets. The sockets were allocated to undergo either (1) ARP and implant placement 8\u00a0weeks later (ARP group) or (2) GBR with simultaneous implant placement after 8\u00a0weeks of unassisted socket healing (GBR group). After an additional healing period of 8\u00a0weeks, bone regeneration and dimensional changes were evaluated radiographically and histologically.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>GBR showed superior bone formation and greater bone gains compared to ARP, regardless of the initial extraction\u2010socket configuration. Although ARP maintained the preexisting alveolar ridge dimensions, peri\u2010implant bone defects were still detected at 8\u00a0weeks of follow\u2010up. Histomorphometric analyses confirmed that GBR increased dimensions of the alveolar ridge compared to baseline, and the augmentation and bone regeneration were greater with GBR than with ARP.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Early implant placement with ARP can mitigate alveolar ridge changes in the narrow alveolar ridge. However, early implant placement with simultaneous GBR creates the conditions for enhanced bone regeneration around the implant and greater ridge augmentation compared to ARP, irrespective of the extraction\u2010socket configuration.<\/jats:p><\/jats:sec>","DOI":"10.1002\/jper.24-0125","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T10:46:41Z","timestamp":1721040401000},"page":"279-289","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["In vivo experimental study comparing alveolar ridge preservation versus guided bone regeneration after unassisted socket healing at intact and damaged sites in narrow alveolar ridges"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4250-4660","authenticated-orcid":false,"given":"Hae Jee","family":"Shin","sequence":"first","affiliation":[{"name":"Department of Periodontology Research Institute of Periodontal 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