{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T12:48:47Z","timestamp":1791809327096,"version":"4.3.4"},"reference-count":134,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Implant prosthetic design significantly impacts peri\u2010implant health. This systematic review and meta\u2010analysis explored emerging concepts in prosthetic considerations, appraising the level of evidence and clinical significance of these suprastructures on peri\u2010implant marginal bone loss (MBL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>An electronic search of three databases and a manual search of peer\u2010reviewed journals for relevant articles published in English between January 1980 and December 2023 were performed. Eligible studies featured dental implants restored within \u226512 months, with \u226510 implants in each group. Inverse variance meta\u2010analyses were performed to compare various prosthetic factors and their impact on MBL and the risk of peri\u2010implantitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Screw\u2010retained versus cement\u2010retained prostheses demonstrated no significant difference in MBL (six articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.51). Nonsplinted implants exhibited lower MBL compared to their splinted counterparts (eight articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.04). Platform\u2010switched abutments were correlated with reduced MBL compared to platform\u2010matched ones (20 articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). Internal connections, particularly conical ones, displayed less MBL than external connections (20 articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). The crown\u2010to\u2010implant ratio did not significantly affect MBL (five articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.32). Abutment heights \u22652\u00a0mm are associated with less MBL than heights &lt;2\u00a0mm (12 articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). Implementing a one abutment\u2010one time protocol resulted in less MBL than repeated abutment disconnections (10 articles,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.0001). Emergence angles &lt;30\u00b0 and a concave\/straight profile led to lower peri\u2010implantitis risk (two articles each;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.05 and\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.03, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nonsplinted implants, platform\u2010switched abutments, abutment heights \u22652\u00a0mm, and a one abutment\u2010one time approach yielded significant reductions in MBL compared to their counterparts. Furthermore, emergence angles &lt;30\u00b0 and a concave\/straight emergence profile were linked to decreased peri\u2010implantitis risk. Meanwhile, factors such as screw\u2010retained versus cement\u2010retained prostheses and crown\u2010to\u2010implant ratio yielded no significant difference in MBL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain Language Summary<\/jats:title>\n                    <jats:p>The design of implant\u2010supported tooth replicas plays a key role in keeping the surrounding gums and bone healthy. This study reviewed research from 1980 to 2023 to examine how different design features of these restorations impact oral tissue health. A total of 93 studies were included, focusing on patients aged 18\u00a0years and older, with at least 10 patients in each group. The findings showed that individual tooth replicas (rather than splinted ones) led to better gum health. A horizontal offset at the implant\u2013replica junction helped reduce bone loss. Implants with internal connections (inside the implant body) performed better than those with external connections. Tooth replicas with narrow contours at the implant junction were more beneficial than convex shapes. Additionally, using abutments taller than 2\u00a0mm and minimizing the number of times an abutment is removed during fabrication helped preserve surrounding tissues. These findings highlight how careful implant design can improve long\u2010term oral health, reducing complications and maintaining stability around dental implants.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.24-0144","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T12:11:02Z","timestamp":1749471062000},"page":"634-651","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["The influence of prosthetic designs on peri\u2010implant bone loss: An AO\/AAP systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"96","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1290-9994","authenticated-orcid":false,"given":"Guo\u2010Hao","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Orofacial Sciences University of California San Francisco School of Dentistry  San Francisco California USA"},{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orofacial Sciences University of California San Francisco School of Dentistry  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5347-6577","authenticated-orcid":false,"given":"Shayan","family":"Barootchi","sequence":"additional","affiliation":[{"name":"Department of Oral Medicine Infection, and Immunity, Harvard University School of Dental Medicine  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Rosen","sequence":"additional","affiliation":[{"name":"Department of Periodontics Rutgers University School of Dental Medicine  Newark New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald","family":"Curtis","sequence":"additional","affiliation":[{"name":"Department of Preventive and Restorative Dental Sciences University of California San Francisco School of Dentistry  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Kan","sequence":"additional","affiliation":[{"name":"Department of Implant Dentistry School of Dentistry Loma Linda University  Loma Linda California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0739"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0000000000000871"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.12738"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.12791"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.3697"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13020"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2008.01627.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2009.090115"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2018.03.004"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100232"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.5140"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2021.09.029"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.6190"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2014.130615"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prosdent.2018.10.003"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2017.170238"},{"key":"e_1_2_11_18_1","first-page":"35","article-title":"One 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