{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T01:52:15Z","timestamp":1775872335913,"version":"3.50.1"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T00:00:00Z","timestamp":1754092800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Herein, we aimed to identify factors associated with tooth loss over a 9\u2010 to 11\u2010year period in young individuals with periodontitis, with a specific focus on the impact of patient compliance. The secondary outcome was to identify factors associated with discontinuation of active periodontal treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective register\u2010based cohort study included 446 patients under the age of 36, diagnosed with periodontitis at 2 periodontal clinics, between 2003 and 2009. Variables were collected from digital dental records combined with 2 national health registers. The follow\u2010up period was between 2009 and 2019. Negative binomial and logistic regression analyses identified factors significantly associated with tooth loss and discontinuation of periodontal treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The majority of patients had lost none or maximum of 3 teeth due to periodontitis, while 3.6% had lost \u2265 10 teeth. The mean number of teeth lost due to periodontitis was 1.3 (range 0\u201326). Generalized periodontitis, stage IV, low level of education, smoking, and discontinuation of active periodontal treatment (APT) were significantly correlated with tooth loss. The variables periodontal stage, low level of education together with low income were correlated to discontinuation of APT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this register\u2010based study, discontinuation of APT, severe periodontal disease, smoking, and low level of education increased the risk for tooth loss. Additionally, low education level, low income, and severe periodontal disease were also significantly associated with discontinuation of APT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>There are few studies focusing on tooth loss in young individuals with periodontitis. To increase knowledge on this issue, this register\u2010based study focused on 446 individuals who were younger than 36 years of age at time of their periodontal diagnosis. During a follow\u2010up period from 2009 to 2019, most individuals lost few or no teeth, while a minority accounted for most of the tooth losses. Patients with a generalized severe periodontal disease, low educational level, and who smoked were at the highest risk of tooth loss. Additionally, interruption of periodontal treatment was observed to be more common in patients with severe disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.24-0687","type":"journal-article","created":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T09:03:17Z","timestamp":1754125397000},"page":"207-219","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors influencing tooth loss over 9\u201311 years in young individuals with periodontitis"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6729-3990","authenticated-orcid":false,"given":"Carolina","family":"Modin","sequence":"first","affiliation":[{"name":"Department of Periodontology Folktandv\u00e5rden Stockholms l\u00e4n AB Folktandv\u00e5rden Eastmaninstitutet Stockholm Sweden"},{"name":"Department of Dental Medicine Division of Periodontology Karolinska Institutet  Huddinge Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3259-2763","authenticated-orcid":false,"given":"Andreas","family":"Cederlund","sequence":"additional","affiliation":[{"name":"Department of Periodontology Folktandv\u00e5rden Stockholms l\u00e4n AB Folktandv\u00e5rden Eastmaninstitutet Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6481-858X","authenticated-orcid":false,"given":"Anders","family":"Gustafsson","sequence":"additional","affiliation":[{"name":"Department of Dental Medicine Division of Periodontology Karolinska Institutet  Huddinge Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0129-8809","authenticated-orcid":false,"given":"T\u00fclay","family":"Yucel\u2010Lindberg","sequence":"additional","affiliation":[{"name":"Department of Dental Medicine Division of Pediatric Dentistry Karolinska Institutet  Huddinge Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5923-5777","authenticated-orcid":false,"given":"Leif E.","family":"Jansson","sequence":"additional","affiliation":[{"name":"Department of Periodontology Folktandv\u00e5rden Stockholms l\u00e4n AB Folktandv\u00e5rden Eastmaninstitutet Stockholm Sweden"},{"name":"Department of Dental Medicine Division of Periodontology Karolinska Institutet  Huddinge Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034514552491"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13266"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1981.tb02039.x"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb02245.x"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2004.75.5.672"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051X.2003.00289.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01184.x"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01698.x"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12266"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12533"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13348"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13553"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12087"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13290"},{"issue":"16","key":"e_1_2_11_16_1","first-page":"S221","article-title":"Effect of professional mechanical plaque removal performed on a long\u2010term, routine basis in the secondary prevention of periodontitis: a systematic review","volume":"42","author":"Trombelli L","year":"2015","journal-title":"J Clin Periodontol"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01708.x"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12271"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12517"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13204"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515578910"},{"issue":"4","key":"e_1_2_11_22_1","first-page":"197","article-title":"Oral health in adolescents with immigrant background in Stockholm","volume":"15","author":"Dahll\u00f6f G","year":"1991","journal-title":"Swed Dent J"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016357.2011.640279"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19-0390"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13489"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13430"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21-0211"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21-0296"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12596"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13884"},{"key":"e_1_2_11_31_1","unstructured":"Socialstyrelsen.Swedish Dental Health Register.https:\/\/www.socialstyrelsen.se\/statistik-och-data\/register\/tandhalsoregistret\/"},{"key":"e_1_2_11_32_1","unstructured":"Longitudinal integrated database for health insurance and labour market studies (LISA);2022.https:\/\/www.scb.se\/en\/services\/ordering-data-and-statistics\/register\/longitudinal-integrated-database-for-health-insurance-and-labour-market-studies-lisa\/"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0721"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.18-0006"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1978.49.5.225"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13225"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12725"},{"key":"e_1_2_11_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13010"},{"key":"e_1_2_11_40_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513501878"},{"key":"e_1_2_11_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13118"},{"key":"e_1_2_11_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.14062"},{"key":"e_1_2_11_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13770"},{"key":"e_1_2_11_44_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1994.65.7.718"},{"key":"e_1_2_11_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2006.00965.x"},{"key":"e_1_2_11_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12063"},{"key":"e_1_2_11_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2018.02.014"},{"key":"e_1_2_11_48_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13240"},{"key":"e_1_2_11_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13336"},{"key":"e_1_2_11_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2011.01733.x"},{"key":"e_1_2_11_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2004.00629.x"},{"key":"e_1_2_11_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13642"},{"key":"e_1_2_11_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12448"},{"key":"e_1_2_11_54_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2018.1539238"},{"key":"e_1_2_11_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3785"},{"key":"e_1_2_11_56_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2016.1259497"},{"key":"e_1_2_11_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11135-006-9018-6"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/JPER.24-0687","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/JPER.24-0687","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/JPER.24-0687","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T11:37:04Z","timestamp":1773920224000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/JPER.24-0687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,2]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1002\/JPER.24-0687"],"URL":"https:\/\/doi.org\/10.1002\/jper.24-0687","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,2]]},"assertion":[{"value":"2024-10-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}