{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T17:39:34Z","timestamp":1787593174728,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T00:00:00Z","timestamp":1766707200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["aap.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal of Periodontology"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Identifying individuals at high risk for developing peri\u2010implantitis (PI) and then determining the prognosis for implants with PI is crucial for treatment planning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study longitudinally followed implants from implant placement retrospectively. The peri\u2010implant disease risk assessment (IDRA) tool was applied, and the performance of the Kwok and Caton (KC) implant prognostication tool was compared with that of a new tool based on the frequency of progressive bone loss (PBL). The predictive accuracy of IDRA, PBL, and KC was evaluated at the corresponding time points (T1\u2013T5). Fisher's exact test was used to evaluate categorical variables, and the Mann\u2010Whitney test was used to evaluate continuous variables. Multiple regression models were built to correlate the occurrence of peri\u2010implantitis and implant survival. The study followed the OHstat and TRIPOD guidelines for reporting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>146 dental implants in 87 patients were included (age\u00a0=\u00a063.19\u00a0\u00b1\u00a011.38 years). IDRA classified the implants as 85.62% high\u2010, 14.38% moderate\u2010, and 0% low\u2010risk. The KC scores showed 7.53% of implants with a favorable\u2010, 65.07% with a questionable\u2010, and 27.4% with an unfavorable prognosis. IDRA showed limited predictive power with an AUC of 0.533 (95% CI: 0.477\u20130.590). The KC tool performed much better, where a score of 2 had an AUC of 0.8321 (95% CI: 0.7257\u20130.9386). PBL yielded a moderate but consistent effectiveness with an AUC of 0.7697 (95% CI: 0.593\u20130.9463).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The KC and PBL prognostication tools exhibited good predictive capability for implant survival, while the IDRA tool demonstrated marginal efficacy in predicting the incidence of peri\u2010implantitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Plain language summary<\/jats:title>\n                    <jats:p>In this study, we followed 87 patients with 146 implants over time to test how well different tools can predict implant health and survival. We tested three tools, IDRA for predicting peri\u2010implantitis, the KC system, and a new tool based on progressive bone loss for predicting implant survival. After 2 years with the implant crowns in place, we checked for cases of peri\u2010implantitis. At the final follow\u2010up (up to 8 years), the implant survival was assessed. We found that IDRA was not effective in predicting which implants developed peri\u2010implantitis, even in high\u2010 and moderate\u2010risk implants. In contrast, the KC tool was much more accurate, predicting implant survival in about 80% of cases. The PBL tool was also good in predicting implant survival, but slightly less accurate than the\u00a0KC tool.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/jper.70047","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T08:46:53Z","timestamp":1766738813000},"page":"1784-1794","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Predicting peri\u2010implantitis incidence and implant failure via risk\u2010assessment and prognostication tools: A validation study"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5067-7317","authenticated-orcid":false,"given":"Muhammad H. A.","family":"Saleh","sequence":"first","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4823-9231","authenticated-orcid":false,"given":"Era","family":"Kakar","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5647-4414","authenticated-orcid":false,"given":"Giuseppe","family":"Troiano","sequence":"additional","affiliation":[{"name":"Department of Medicine and Surgery University LUM  Casamassima Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-0804-2729","authenticated-orcid":false,"given":"Hamzeh","family":"Almashni","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Misch","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1820-899X","authenticated-orcid":false,"given":"Fariba","family":"Esperouz","sequence":"additional","affiliation":[{"name":"Department of Clinical and Experimental Medicine University of Foggia  Foggia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2112-2804","authenticated-orcid":false,"given":"Shahad","family":"Alhazmi","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4238-1799","authenticated-orcid":false,"given":"Hom\u2010Lay","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0636-6313","authenticated-orcid":false,"given":"Zolt\u00e1n","family":"Bar\u00e1th","sequence":"additional","affiliation":[{"name":"Department of Periodontology University of Szeged  Szeged Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9368-4047","authenticated-orcid":false,"given":"Istvan A.","family":"Urban","sequence":"additional","affiliation":[{"name":"Department of Periodontics and Oral Medicine University of Michigan School of Dentistry  Ann Arbor Michigan USA"},{"name":"Department of Periodontology University of Szeged  Szeged Hungary"},{"name":"Graduate Implant Dentistry Loma Linda University Loma Linda California USA"},{"name":"Urban Regeneration Institute  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12335"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00803.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12350"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2008.01283.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01667.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.11607\/jomi.2013.g5"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13585"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13828"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2023.104630"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13371"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12535"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0739"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034520944158"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12418"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12568"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.070210"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.22-0196"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13102"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.20-0124"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.13542"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.20-0662"},{"key":"e_1_2_10_23_1","unstructured":"World Medical Association.World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. Accessed March 23 2023. Available at:https:\/\/www.wma.net\/policies-post\/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects\/"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.281053"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2024.06.007"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2024.06.006"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0697"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.7326\/M14-0698"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17-0588"},{"key":"e_1_2_10_30_1","first-page":"8","article-title":"Interpretation of radiographs in periodontics","volume":"3","author":"Prichard JF","year":"1983","journal-title":"Int J Periodontics Restorative Dent"},{"key":"e_1_2_10_31_1","unstructured":"National Center for Health Statistics.Table A\u201312a. Age\u2010adjusted percentages (with standard errors) of current cigarette smoking status among adults aged 18 and over by selected characteristics: United States 2018. Summary Health Statistics Tables: National Health Interview Survey 2018. Accessed October 26 2025.https:\/\/ftp.cdc.gov\/pub\/Health_Statistics\/NCHS\/NHIS\/SHS\/2018_SHS_Table_A-12.pdf"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12577"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12491"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0501.2010.01912.x"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.2014.28"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13828"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb00852.x"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2024.05.002"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.21-0723"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.22-0499"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-160X-10-34"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12334"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/cid.13155"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.24\u20100376"},{"key":"e_1_2_10_45_1","first-page":"73","article-title":"Peri\u2010implant tissue stability: the PROS concept","volume":"18","author":"Misch J","year":"2025","journal-title":"Int J Oral Implantol (Berl)"},{"key":"e_1_2_10_46_1","first-page":"416","article-title":"A prognosis system for periimplant diseases","volume":"24","author":"Decker AM","year":"2015","journal-title":"Implant Dent"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.5876"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/ID.0b013e3182263589"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.11607\/prd.2996"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/clr.13290"}],"container-title":["Journal of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jper.70047","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/jper.70047","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/jper.70047","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T17:16:57Z","timestamp":1787591817000},"score":1,"resource":{"primary":{"URL":"https:\/\/aap.onlinelibrary.wiley.com\/doi\/10.1002\/jper.70047"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,26]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1002\/jper.70047"],"URL":"https:\/\/doi.org\/10.1002\/jper.70047","archive":["Portico"],"relation":{},"ISSN":["0022-3492","1943-3670"],"issn-type":[{"value":"0022-3492","type":"print"},{"value":"1943-3670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,26]]},"assertion":[{"value":"2025-03-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}